Targeted Drug Delivery Mechanism

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ENDOCYTIC MECHANISMS FOR TARGETED DRUG DELIVERY

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2000329/
    Aug 10, 2007 · For example, targeted drug delivery strategies have exploited the clathrin-dependent receptor mediated endocytic events of glycoreceptors, including mannose-6-phosphate receptor and mannose receptor . This delivery mechanism provokes a highly directed method for the delivery of deficient lysosomal enzymes as well as drug precursors.Author: Lisa M. Bareford, Peter W. Swaan

Catechol Polymers for pH-Responsive, Targeted Drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149454/
    Aug 10, 2011 · This work has demonstrated targeted delivery of an anticancer drug to cancer cells using catechol-presenting polymers. These polymeric drug carriers have a chemically defined mechanism for drug loading and release through the pH-sensitive catechol–boronic acid interaction.Author: Jing Su, Feng Chen, Vincent L. Cryns, Phillip B. Messersmith

Nano based drug delivery systems: recent developments and ...

    https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
    Sep 19, 2018 · Likewise, compact lipid nanostructures and phospholipids including liposomes and micelles are very useful in targeted drug delivery. The use of ideal nano-drug delivery system is decided primarily based on the biophysical and biochemical properties of the targeted drugs being selected for the treatment . However, problems such as toxicity ...Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...

Efficient lung cancer-targeted drug delivery via a ...

    https://www.sciencedirect.com/science/article/pii/S221138351830296X
    In vivo assays showed that the MSC/NP/DTX drug delivery system exerted primary tumor inhibition efficiency similar to that of a NP/DTX drug system. Collectively, the MSC/NP drug delivery system is promising for lung-targeted drug delivery for the treatment of lung cancer and other lung-related diseases.Author: Xusheng Wang, Haiyan Chen, Xiaowei Zeng, Wenpeng Guo, Yu Jin, Shan Wang, Ruiyun Tian, Yanjiang Han, ...

Targeted Drug Delivery System - YouTube

    https://www.youtube.com/watch?v=Up0RclkzeOY
    May 04, 2017 · This Video describes about how liposomes acts as drug carriers in targeted drug delivery system.Author: Chakka Tharun

Construction of redox-responsive tumor targeted cisplatin ...

    https://www.sciencedirect.com/science/article/pii/S0378517320301745
    Herein, a tumor targeted and GSH-cleavable stimuli responsive nano-delivery system for cisplatin was constructed using branched polyethyleneimine (BPEI) as the backbone, disulfide bond as the redox-responsive covalent linker and hyaluronic acid (HA) as the targeting moiety which can selectively bind to the CD44 receptor that is highly expressed on tumor cells (Choi et al., 2019, Bae et al., 2017).Author: Yi-Yang Jia, Jun-Jie Zhang, Ya-Xuan Zhang, Wei Wang, Chen Li, Si-Yuan Zhou, Bang-Le Zhang

(PDF) Designing Polymeric Nanoparticles for Targeted Drug ...

    https://www.researchgate.net/publication/280858357_Designing_Polymeric_Nanoparticles_for_Targeted_Drug_Delivery_System
    Designing Polymeric Nanoparticles for Targeted Drug Delivery System Chapter (PDF Available) · December 2014 with 3,826 Reads How we measure 'reads'

Ligand-Targeted Drug Delivery Chemical Reviews

    https://pubs.acs.org/doi/10.1021/acs.chemrev.7b00013
    Safety and efficacy constitute the major criteria governing regulatory approval of any new drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic agent with a targeting ligand that exhibits little affinity for healthy cells but high affinity for pathologic cells. The probability of regulatory approval can conceivably be further enhanced by exploiting the same ...Author: Madduri Srinivasarao, Philip S. Low

Targeted drug delivery for cancer therapy: the other side ...

    https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-5-70
    Nov 09, 2012 · In view of the recognized importance of targeted drug delivery strategies for cancer therapy, we discuss the advantages of alternative drug carriers and where these should be applied, focusing on peptide-drug conjugates (PDCs), particularly …Author: Michael A Firer, Gary Gellerman

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