Targeted Drug Delivery Dendrimers

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Dendrimers in drug delivery and targeting: Drug-dendrimer ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
    FA conjugated G5 PAMAM dendrimers for the targeted delivery of 2-methoxyestradiol to cancer cells, as confirmed by MTT assay, were recently reported. Sideratou et al. prepared folate functionalized PEG coated nanocarrier based on fourth generation diaminobutane PPI dendrimers …

Dendrimer-based targeted drug delivery - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/B9780128145272000056
    Presently the use of dendrimers in targeted drug delivery is on wheels. The in-depth in vitro and in vivo studies of many research groups have enlightened that targeted dendrimers formulations have performed better than non-targeted formulations in the treatment of many serious diseases and disorders.Author: Lakshmi Tunki, Hitesh Kulhari, Ramakrishna Sistla, Deep Pooja

Targeted drug delivery with dendrimers: Comparison of the ...

    https://www.sciencedirect.com/science/article/pii/S0169409X05001948
    Dec 14, 2005 · 1. Introduction. Targeted drug delivery directs a therapeutic agent in a site-specific manner to a particular cell type or tissue. It could be beneficial in cancer therapy where cytotoxic drugs can kill tumor cells while sparing healthy tissue overcoming the …Author: Anil K. Patri, Jolanta F. Kukowska-Latallo, James R. Baker

Dendrimers for Drug Delivery - ncbi.nlm.nih.gov

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017392/
    Apr 18, 2018 · Multiple drug delivery systems: PAMAM dendrimers were evaluated to explore the potential of PAMAM dendrimers for multiple drug delivery. We have entrapped two anti-hypertensive drugs Ramipril (RAPL) and hydrochlorothiazide (HCTZ ). The results showed that the solubility of RAPL and HCTZ was dependent on dendrimer concentrations and pH of ...Author: Abhay Singh Chauhan

Folate and Folate−PEG−PAMAM Dendrimers: Synthesis ...

    https://pubs.acs.org/doi/10.1021/bc800125u
    Ligand-mediated targeting of drugs especially in anticancer drug delivery is an effective approach. Dendrimers, due to unique surface topologies, can be a choice in this context. In the present study, PAMAM (polyamidoamine) dendrimers up to fourth generation were synthesized and characterized through infrared (IR), nuclear magnetic resonance (NMR), electrospray ionization (ESI) mass ...Author: Prateek Singh, Umesh Gupta, Abhay Asthana, Narendra K. Jain

(PDF) Targeted Drug Delivery: A Review - ResearchGate

    https://www.researchgate.net/publication/297283078_Targeted_Drug_Delivery_A_Review
    Targeted drug delivery, also known as smart drug delivery, is a method of treatment that involves the increase in medicament in one or few body parts in comparison to others. Two strategies are

Targeted therapy in chronic diseases using nanomaterial ...

    https://www.nature.com/articles/s41392-019-0068-3
    Aug 30, 2019 · A variety of drug delivery vehicles have been established for the targeted and controlled delivery of therapeutic agents in a wide range of chronic diseases, such as diabetes, cancer ...Author: Akhand Pratap Singh, Arpan Biswas, Aparna Shukla, Pralay Maiti

(PDF) Dendrimer as nanocarrier for drug delivery

    https://www.researchgate.net/publication/260028945_Dendrimer_as_nanocarrier_for_drug_delivery
    Dendrimer as nanocarrier for drug delivery. ... the contribution of dendrimers in the field of nanotechnology with intent to aid the researchers in exploring dendrimers in the field of drug delivery.

Peptide- and saccharide-conjugated dendrimers for targeted ...

    https://royalsocietypublishing.org/doi/10.1098/rsfs.2012.0009
    Mar 21, 2012 · For drug delivery purposes, dendrimers may serve at least two functions in the drug delivery process: to carry drug molecules and transport them to the diseased tissue; and to present bioactive ligands to enable targeted cellular interactions. This allows the cargo to overcome biological barriers encountered in drug transport in vivo.Author: Jie Liu, Warren D. Gray, Warren D. Gray, Michael E. Davis, Michael E. Davis, Michael E. Davis, Ying ...

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