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https://pubs.acs.org/doi/abs/10.1021/bc2006219
Chitosan has frequently been used in gene delivery applications, including siRNA delivery. However, studies regarding the modification of chitosan with antibodies specifically targeting T cells are lacking. We hypothesized that chitosan nanoparticles modified with T cell-specific antibodies would be useful for delivering siRNA to T cells.Author: Jangwook Lee, Kyoung-Soo Yun, Chang Seon Choi, Seung-Hwa Shin, Hong-Seok Ban, Taiyoun Rhim, Sang Kyu...
https://www.researchgate.net/publication/225046914_T_Cell-Specific_siRNA_Delivery_Using_Antibody-Conjugated_Chitosan_Nanoparticles
T Cell-Specific siRNA Delivery Using Antibody-Conjugated Chitosan Nanoparticles Article in Bioconjugate Chemistry 23(6) · May 2012 with 175 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/S0141813018371265
Cationic nanoparticles were synthesized as siRNA carriers to silence HIV-1 genes in target cells. Depolymerization of chitosan 400 kDa to the chitosan 18 kDa (Ch18) was performed according to a previously reported method [] and the average Mw of chitosan was calculated by using viscometric method.The stock solution of chitosan (1.5 mg/mL) was prepared by dissolving Ch18 in distilled …Author: Vahid Iranpur Mobarakeh, Mohammad Hossein Modarressi, Mohammad Hossein Modarressi, Pooneh Rahimi, Az...
https://www.sciencedirect.com/science/article/pii/S0927776514001222
To address the above challenges, herein we present a novel design of CUR nano-formulation using both CD and CS as excipients ().In the first step, we develop a simple and scalable spray drying method for the preparation of CUR-CD hollow particles with high solubility (Scheme 1A).Highly soluble CUR-CD system makes it possible for its encapsulation in CS nanoparticles (CUR-CD-CS) with the aid of ...Author: Amirali Popat, Surajit Karmakar, Siddharth Jambhrunkar, Chun Xu, Chengzhong Yu
https://www.researchgate.net/publication/23160423_T_Cell-Specific_siRNA_Delivery_Suppresses_HIV-1_Infection_in_Humanized_Mice
T Cell-Specific siRNA Delivery Suppresses HIV-1 Infection in Humanized Mice ... for T cell-specific siRNA delivery in NOD/SCIDIL2rgamma-/- mice reconstituted with human lymphocytes (Hu-PBL) or ...
https://onlinelibrary.wiley.com/doi/10.1002/anie.200805998
All‐in‐One Target‐Cell‐Specific Magnetic Nanoparticles for ... Sun Hwa Kim and Ick Chan Kwon, Tumor‐Targeting Multifunctional Nanoparticles for siRNA Delivery: Recent ... , Heebeom Koo, Dong Eun Lee, Kuiwon Choi, Ick Chan Kwon and Kwangmeyung Kim, Multifunctional Chitosan Nanoparticles for Tumor Imaging and ...Author: Jh Lee Jae-Hyun Lee, Kr Lee Kyu-Ri Lee, Sh Moon Seung-Ho Moon, Yh Lee Yu-Han Lee, Tg Park Tae-Gwan P...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3644528/
Immunotherapy is a promising approach for treating cancer. However, there are limitations inherent to current approaches which may be addressed by integrating them with biomaterial-based strategies. ... T Cell-Specific siRNA Delivery Using Antibody-Conjugated Chitosan Nanoparticles. Bioconjug Chem. 2012 . 28. Uto T, Akagi T, Yoshinaga K, Toyama ...Author: Weiwei Aileen Li, Weiwei Aileen Li, David J Mooney, David J Mooney
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042134/
Jun 26, 2018 · Lee J, et al. T cell-specific siRNA delivery using antibody-conjugated chitosan nanoparticles. Bioconjug Chem. 2012; 23:1174–1180. [Google Scholar] 31. Schallon A, Synatschke CV, Jérôme V, Müller AHE, Freitag R. Nanoparticulate nonviral agent for the effective delivery of pDNA and siRNA to differentiated cells and primary human T ...Author: Colin J. McKinlay, Nancy L. Benner, Ole A. Haabeth, Robert M. Waymouth, Paul A. Wender
https://www.nbl-hyu.com/publication
H. J. Jang, E. J. Jeong, K. Y. Lee, "Carbon Dioxide-Generating PLG Nanoparticles for Controlled Anti-Cancer Drug Delivery", Pharmaceutical Research, submitted (2018).
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