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https://www.annualreviews.org/doi/abs/10.1146/annurev.cb.07.110191.002403
T-Cell Effector Functions: Mechanisms for Delivery of Cytotoxicity and Help. Annual Review of Cell Biology Vol. 7:479-504 (Volume publication date November 1991) ... Macroautophagy is mediated by a unique organelle, the autophagosome, which encloses a portion of cytoplasm for delivery to the lysosome. Autophagosome formation is dynamically ...Author: Eckhard R. Podack, Abraham Kupfer
https://www.annualreviews.org/doi/10.1146/annurev.cb.07.110191.002403
T Cell Activation Jennifer E. Smith-Garvin, Gary A. Koretzky, and Martha S. Jordan Annual Review of Immunology Replication and Transcription of Vertebrate Mitochondrial DNA David A. Clayton Annual Review of Cell Biology Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance Federica Sallusto, Jens Geginat, and Antonio LanzavecchiaAuthor: Eckhard R. Podack, Abraham Kupfer
https://www.cell.com/immunity/fulltext/S1074-7613(17)30463-6
Nov 21, 2017 · CD4 + T cells optimize the cytotoxic T cell (CTL) response in magnitude and quality, by unknown molecular mechanisms. We here present the transcriptomic changes in CTLs resulting from CD4 + T cell help after anti-cancer vaccination or virus infection. The gene expression signatures revealed that CD4 + T cell help during priming optimized CTLs in expression of cytotoxic effector …Author: Tomasz Ahrends, Aldo Spanjaard, Bas Pilzecker, Nikolina Bąbała, Astrid Bovens, Yanling Xiao, Heinz J...
https://www.ncbi.nlm.nih.gov/books/NBK27149/
All T-cell effector functions involve the interaction of an armed effector T cell with a target cell displaying specific antigen. The effector proteins released by these T cells are focused on the appropriate target cell by mechanisms that are activated by recognition of antigen on the target cell. The focusing mechanism is common to all types of effector T cells, whereas their effector ...Author: Charles A Janeway, Paul Travers, Mark Walport, Mark J Shlomchik
https://www.cell.com/fulltext/S0092-8674(00)80309-8
Crosslinking of NKR leads to inhibition of different TCR-dependent and TCR-independent (e.g., NK-like cytotoxicity) T cell functions. The inhibitory effect exerted on TCR-mediated functions has important implications. Thus, the expression of inhibitory NKR may result in functional impairment of specific CTLs.Author: Alessandro Moretta
https://quizlet.com/129554330/unit-2-effector-t-cells-and-their-functions-flash-cards/
Unit 2- Effector T cells and their Functions study guide by blougee29 includes 68 questions covering vocabulary, terms and more. Quizlet flashcards, activities and games help you improve your grades.
https://www.sciencedirect.com/science/article/pii/B9780123852458000091
E. Termination of Effector T Cell Responses. The Th effector cells and CTLs that are actively proliferating and employed in eliminating a pathogen that sparked a primary immune response are sustained by signals delivered by inflammatory cytokines (such as IL-12) and transcription factors (such as …
https://quizlet.com/25625784/effector-functions-cell-mediated-immunity-flash-cards/
Have no effector functions until they are activated Only activated in the periphery lymphoid organs antigen is high for B cells, and DC cells are present for T cell activation ***DC cells are the only APC cells that express enough MHC, costim, and cytokines (IL-12) to activate a NAIVE cell
https://www.sciencedirect.com/science/article/pii/0952791593900606
Cell-mediated cytotoxicity: contact and secreted factors Sergei Apasov, Frank Redegeld and Michail Sitkovsky National Institutes of Health, Bethesda, USA The list of cells with cytotoxic potential now may include small resting T cells, but the exact nature of 'lethal hit delivery…Author: Sergei Apasov, Frank Redegeld, Michail Sitkovsky
https://www.ncbi.nlm.nih.gov/books/NBK27101/
T cell-mediated cytotoxicity. All viruses, and some bacteria, multiply in the cytoplasm of infected cells; indeed, the virus is a highly sophisticated parasite that has no biosynthetic or metabolic apparatus of its own and, in consequence, can replicate only inside cells. Once inside cells, these pathogens are not accessible to antibodies and ...Author: Charles A Janeway, Paul Travers, Mark Walport, Mark J Shlomchik
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