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https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021623lbl.pdf
simultaneous applications of Synera patches on intact skin. Maximum plasma levels of lidocaine after the application of a) four successive Synera patches for 30 minutes each with a 30-minute...
http://staging.synera.com/
SYNERA ® is a simple-to-use patch that safely and effectively helps prevent pain associated with certain needle-stick procedures. 1. In clinical studies involving 1,449 subjects treated with SYNERA ®, the most common local reactions were redness of the skin (71%), pale skin (12%) and swelling (12%); these reactions were generally mild and ...
https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021623s015s017lbl.pdf
SYNERA topical patch contains 70 mg lidocaine and 70 mg tetracaine, has a total skin contact area of 50 cm, and an active drug-containing area of 10 cm. 2 . 4 Contraindications • SYNERA is contraindicated in patients with a known history of sensitivity to lidocaine, tetracaine, or …
http://staging.synera.com/pediatric-patients/
SYNERA ® is the easy-to-use, peel-and-stick patch that uses a gentle warming technology that is proven to better deliver two common pain-reducing numbing medications (lidocaine and tetracaine) into the skin. 1 Worn for only 20 to 30 minutes, SYNERA ® numbs the …
https://www.rxlist.com/synera-drug.htm
Maximum plasma levels of lidocaine after the application of a) four successive SYNERA patches for 30 minutes each with a 30-minute interval between each patch application, and b) three SYNERA patches for 60 minutes each with a 60-minute interval between each application were less than 12 ng/mL and 8 ng/mL, respectively.
https://www.pdr.net/drug-summary/Synera-lidocaine-tetracaine-1174
As determined by a pinprick test in 40 adults, the median duration of analgesia was 11 hours after 30 or 60 minutes of application of the cream. The mean time for return of sensation was similar between the 30- and 60-minute application periods.
https://www.synera.com.au/
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https://www.drugs.com/synera.html
Synera patches are also used to numb a skin area during minor cosmetic procedures such as a Botox injection, laser treatment, or tattoo removal. Warnings An overdose of numbing medicine can cause fatal side effects if too much of the medicine is absorbed through your skin.
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