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https://www.cdc.gov/stroke/treatments.htm
If you get to the hospital within 3 hours of the first symptoms of an ischemic stroke, you may get a type of medicine called a thrombolytic (a “clot-busting” drug) to break up blood clots. Tissue plasminogen activator (tPA) is a thrombolytic.
https://pubmed.ncbi.nlm.nih.gov/11988629/
Background: The use of recombinant tissue plasminogen activator (rtPA) within 3 hours after onset of an ischemic stroke is an established therapy. Because the use of intravenous rtPA beyond a time window of 3 hours after stroke onset is still a matter of debate, we sought to review the evidence for the use of thrombolytic therapy in a time window up to 6 hours after …
https://www.dailymail.co.uk/health/article-1278172/Stroke-victims-hour-window-clot-busting-drug-Alteplase.html
Stroke victims have 'three-hour window' to take clot-busting drug to boost chance of full recovery. By Jenny Hope for the Daily Mail. Updated: 05:02 EDT, 14 May 2010. Stroke victims who take clot...
https://www.ninds.nih.gov/About-NINDS/Impact/NINDS-Contributions-Approved-Therapies/Tissue-Plasminogen-Activator-Acute
When administered quickly after stroke onset (within three hours, as approved by the FDA), tPA helps to restore blood flow to brain regions affected by a stroke, thereby limiting the risk of damage and functional impairment.
https://www.webmd.com/stroke/news/20000229/stroke-medication-effective-when-given-properly
The catch with tPA is that it must be administered within three hours of the first symptom of a stroke to reduce the chance of further brain damage.
https://www.nhs.uk/conditions/stroke/treatment/
Ischaemic strokes can often be treated using injections of a medicine called alteplase, which dissolves blood clots and restores blood flow to the brain. This use of "clot-busting" medicine is known as thrombolysis. Alteplase is most effective if started as soon as possible after the stroke occurs – and certainly within 4.5 hours.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3152174/
All patients with disabling acute ischemic stroke who can be treated within 3 hours (4.5 hours as soon as approved by the Drug Controlling authority) after symptom onset should be evaluated without delay to determine their eligibility for treatment with intravenous tissue plasminogen activator (alteplase).
https://www.tuftsmedicalcenter.org/patient-care-services/Departments-and-Services/Neurology/Clinical-Care-Services/Stroke-Center/24-to-48-Hours-After-Stroke
The First 24 to 48 Hours. If you or a loved one is having a stroke, it is incredibly important that you receive medical attention right away. Immediate treatment can minimize the long-term impact of stroke: stroke can be disabling or life-threatening. During the first 24-48 hours, your doctors and nurses will be working together to stabilize ...
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