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https://pubmed.ncbi.nlm.nih.gov/32430395/
Objectives: Alteplase is commonly recommended for acute ischaemic stroke within 4.5 hours after stroke onset. The Third European Cooperative Acute Stroke Study (ECASS III) is the only trial reporting statistically significant efficacy for clinical outcomes for alteplase use 3-4.5 hours after stroke onset.Cited by: 6
https://st-patricks.org/funeral/stanton-mcmasters-smith-iii/
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https://ebm.bmj.com/content/ebmed/early/2020/05/18/bmjebm-2020-111386.full.pdf
May 18, 2020 · III trial, most clinical practice guidelines for the management of acute ischaemic stroke currently recommend extending the use of alteplase up to 4.5 hours after stroke onset.2–12 To date, ECASS III is the only trial to have reported benefit from use of alteplase 3–4.5 hours after stroke onset.
https://cases.justia.com/california/court-of-appeal-3rd-appellate-district/C058539.PDF?ts=1396114182
ratio. Scott estimated she spent 10 to 15 minutes with Juanita McMaster. Scott told McMaster there was currently no space for her child, but that there would be space available in a couple of weeks, and put her daughter‟s name on a waiting list. Juanita McMaster came back to the Rocklin school with her husband a couple of days later.
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