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https://www.sciencedirect.com/science/article/pii/B9780128136690000075
Synthesis of Dendrimer-Drug Conjugates by Amide Linkage A drug molecule containing a carboxylic or amine group can be conjugated to dendrimers through an amide link. Amide linkage is highly stable at physiological conditions and provides the advantage of improved pharmacokinetics by prolonging the duration in the blood circulation.Author: Deep Pooja, Ramakrishna Sistla, Hitesh Kulhari, Hitesh Kulhari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4097927/
Dendrimers are the emerging polymeric architectures that are known for their defined structures, versatility in drug delivery and high functionality whose properties resemble with biomolecules.
https://www.researchgate.net/publication/5858244_Synthesis_of_dendrimers_and_drug-dendrimer_conjugates_for_drug_delivery
While drug- dendrimer conjugates have been developed as pro-drugs [35], the VivaGel ® product appears to exert its activity through binding of the highly negatively charged surface Brought to you ...
https://pubs.rsc.org/en/content/articlelanding/2012/jm/c2jm16792a#!
Synthesis and characterization of DOX-conjugated dendrimer-modified magnetic iron oxide conjugates for magnetic resonance imaging, targeting, and drug delivery Yulei Chang , a Nian Liu , b Liang Chen , c Xinlei Meng , a Yanjing Liu , d Yapeng Li * a and Jingyuan Wang a
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074873/
May 21, 2014 · Dendrimers have found applications in transdermal drug delivery systems. Generally, in bioactive drugs having hydrophobic moieties in their structure and low water solubility, dendrimers are a good choice in the field of efficient delivery system [ 63 ].Author: Elham Abbasi, Sedigheh Fekri Aval, Abolfazl Akbarzadeh, Morteza Milani, Hamid Tayefi Nasrabadi, Sang...
https://www.researchgate.net/publication/230235723_Dendrimer_Conjugates_for_Drug_Delivery
Dendrimer Conjugates for Drug Delivery. ... Intercepting the synthesis of triazine dendrimers with nucleophilic pharmacophores: A general strategy toward drug delivery vehicles.
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