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https://www.sciencedirect.com/science/article/pii/S0960894X09008233
Metastatic bone disease is often associated with bone pain, pathologic fractures, and nerve compression syndromes. Effective therapies to inhibit the progression of bone metastases would have important clinical benefits. Therefore, we developed a novel calcium phosphate-binding liposome for a bone-targeting drug delivery system.Author: Takahisa Anada, Yoichi Takeda, Yoshitomo Honda, Kazuo Sakurai, Osamu Suzuki
https://www.researchgate.net/publication/26289620_Synthesis_of_calcium_phosphate-binding_liposome_for_drug_delivery
Request PDF Synthesis of calcium phosphate-binding liposome for drug delivery Metastatic bone disease is often associated with bone pain, pathologic fractures, and nerve compression syndromes.
https://www.academia.edu/624693/Synthesis_of_calcium_phosphate-binding_liposome_for_drug_delivery
Synthesis of calcium phosphate-binding liposome for drug delivery
https://www.sciencedirect.com/science/article/pii/S0009308419300957
A novel bone-targeted glutamic oligopeptides-RGD peptide (Glu 6-RGD) derivative was designed and synthesized as liposome ligand. • The preliminary evaluation in vivo demonstrated that ligand Glu 6-RGD-coated liposome had an improved targeting ability. • Glu 6-RGD could act as a vector to enhance the delivery of drugs bone metastasis.Author: Ze Zhao, Yi Zhao, Changwei Xie, Changqing Chen, Dong Lin, Sheng Wang, Xinhua Cui, Zhongshuai Guo, Ju...
https://www.sciencedirect.com/science/article/pii/S0272884211006833
The aim of this paper is to synthesise calcium phosphate (CaP) nanoshells by controlling their particle size and shape using negatively charged liposomes (1,2 dioleoyl-sn-glycero-3 phosphate sodium salt (DOPA) and 1,2-dipalmitoyl-sn-glycero-3-phosphate sodium salt (DPPA)) as a template.The morphology, particle size, size distribution and zeta potential properties of DOPA and DPPA liposome ...Author: Chiew-Hwee Yeo, Sharif Hussein Sharif Zein, Abdul Latif Ahmad, David S. McPhail
https://academic.oup.com/rb/article/3/3/187/1752885
As Figure 3 shows, Huang and his group undertook an in-depth study on CaP modified with liposome for siRNA delivery for many years. At the beginning, they developed lipid-coated calcium phosphate (LCP) nanoparticles, which they called LCP-I afterwards, for efficient delivery of siRNA to a xenograft tumor model by intravenous administration [ 77].Author: Xiaochun Xu, Zehao Li, Xueqin Zhao, Lawrence Keen, Xiangdong Kong
https://www.selleckchem.com/blog/Development-Of-Novel-Liposome-Encapsulated-Combretastatin-A4-Acylated-Derivatives-Prodrug-Approach-For-Improving-Antitumor-Efficacy.html
The liposome system with loaded CA4 derivatives was successfully developed with nano-size and electronegative particles. The rate of in vitro drug release and conversion was reduced as the fatty acid carbon chain lengthened. On the contrary, in vivo antitumor effects were improved with the enlargement of the fatty acid carbon chain.
https://www.sciencedirect.com/science/article/pii/S2211383517307311
Well-known as a gelling agent 88, pectin has also been studied as a stabilizer for liposomal drug delivery systems 89. Low- and high-methoxylated pectins show improved liposomal stability upon storage without disturbing membrane permeability 89. Among various polysaccharides, chitosan may be the choice of coating materials because it is positively charged and readily interacts with the negatively charged liposomal …Author: Haisheng He, Yi Lu, Jianping Qi, Quangang Zhu, Zhongjian Chen, Wei Wu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599573/
Feb 22, 2013 · Liposomal encapsulation technology (LET) is the newest delivery technique used by medical investigators to transmit drugs that act as curative promoters to the assured body organs. This form of delivery system proposal targeted the delivery of vital combinations to the body.Author: Abolfazl Akbarzadeh, Rogaie Rezaei-Sadabady, Rogaie Rezaei-Sadabady, Soodabeh Davaran, Sang Woo Joo,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · Conventional liposomal formulations reduced the toxicity of compounds in vivo, through modifying pharmacokinetics and biodistribution to enhance drug delivery to diseased tissue in comparison to free drug. However, the delivery system was …Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
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