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https://www.mdpi.com/journal/pharmaceutics/special_issues/surfactant_based_drug_delivery
Surfactants function in the same roles as in other industries, ranging from solubilizers to lubricants, wetting agents, emulsifiers/suspending agents, disinfectants, and so on; however, the importance of surfactants in the design of novel drug delivery systems makes this …
https://www.amazon.com/Surfactants-Polymers-Delivery-Pharmaceutical-Sciences/dp/0824708040
-PharmaTimes "well-written and well-documentedvaluable.strongly recommended as an introduction to the physical chemistry of surfactants and polymers for drug delivery." -Angewandte Chemie "an excellent review of the important role that surfactants and polymers play in modern drug delivery."Author: Martin Malmsten
https://www.ncbi.nlm.nih.gov/pubmed/22833979
The main use attributed to surfactants in pulmonary drug delivery is as absorption enhancers by mechanisms of action not yet fully understood. Furthermore, surfactants have been used to improve the delivery of inhaled drugs in various additional strategies discussed herein.Author: Javier O. Morales, Jay I. Peters, Robert O. Williams
https://www.sciencedirect.com/science/article/pii/S0168365918305832
Despite constituting less than 10% of the total surfactant mass, SPs have demonstrated substantial impact on various key steps in the drug delivery process, including the modulation of pulmonary distribution of drugs and drug carriers (e.g. nanomedicines), promoting cellular uptake and targeting of nanomedicines as well as enhancing intracellular delivery of membrane-impermeable therapeutics.Author: Roberta Guagliardo, Jesús Pérez-Gil, Stefaan De Smedt, Koen Raemdonck
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283952/
Surfactants ranging from hydrophobic agents such as oleic acid to hydrophilic sodium lauryl sulfate have been tested as permeation enhancer to improve drug delivery. This article reviews the status of surfactants as permeation enhancer in transdermal drug delivery of various drugs.
https://en.wikipedia.org/wiki/Nanoparticles_for_drug_delivery_to_the_brain
Nanoparticles for drug delivery to the brain is a method for transporting drug molecules across the blood–brain barrier (BBB) using nanoparticles. These drugs cross the BBB and deliver pharmaceuticals to the brain for therapeutic treatment of neurological disorders.
https://www.sciencedirect.com/science/article/pii/S0168365901002991
In broad terms, the solubilization of drugs using micelle-forming surfactants (which results in formation of mixed micelles) might be advantageous for drug delivery purposes because of either increased water solubility of sparingly soluble drug or enhanced permeability across the physiological barrier or substantial changes in the drug biodistribution.Author: Vladimir P. Torchilin
https://www.pharmatutor.org/articles/surfactants-and-its-applications-in-pharmaceuticals-overview
Fig.no.1. Surfactant (Monomer) Head - Polar, Hydrophilic Tail - Non polar, Hydrophobic • Adsorption Phenomena of Surfactant [2] Adsorption may be defined as the process of enrichment of one or more substances at a surface or as the taking up of one substance at the surface of another. It can occur at any type of interface.
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