Surface Mediated Drug Delivery

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Drug Releasing Polymer Thin Films: New Era of Surface ...

    https://pubs.acs.org/doi/10.1021/nn100634r
    Polymer films and coatings are among the popular and most successful tools to modulate surface properties of biomaterials, specifically tissue responses and fouling behavior. Over the past decade, a novel opportunity has been widely investigated, namely utility of surface coatings in surface-mediated drug delivery. In these applications, deposited polymer films act as both a coating to ...Author: Alexander N. Zelikin

Nanoparticle-Mediated Pulmonary Drug Delivery: A Review

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013600/
    Apr 08, 2014 · Nanoparticle-mediated drug delivery systems open new perspectives by modifying the physical properties of the particles, such as increasing the drug solubility, encapsulation efficacy and surface alterations to enhance the drug release profiles and to obtain a maximum effect [11 ...Author: Mukta Paranjpe, Christel C. Müller-Goymann

Cell-Mediated Drugs Delivery - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062753/
    Consequently, design of nanocarriers for cell-mediated drug delivery (size, shape, surface charge, etc.) may differ from those used for conventional drug delivery systems. Nevertheless, engaging different defense mechanisms into drug delivery may open a new perspective of active delivery of drugs for treatment of various devastating diseases.Author: Elena V. Batrakova, Howard Eliot Gendelman, Alexander V. Kabanov

Surface engineering of nanoparticles with ligands for ...

    https://www.sciencedirect.com/science/article/pii/S0927776520301211
    Nowadays, nanoparticle-mediated targeted drug delivery system (NTDDS) is widely used in osteosarcoma. The NTDDS includes a therapeutic agent, a delivery vehicle and a surface ligand that mediates cell internalization into tumor cells [10,11].Author: Xin Huang, Wei Wu, Wenbo Yang, Xiangcheng Qing, Zengwu Shao

Nanoparticle-mediated targeted drug delivery for breast ...

    https://www.sciencedirect.com/science/article/pii/S0304419X19300332
    Wu et al. introduced a NPs-mediated drug delivery system (DDS) conjugated with RGD ligand, which shows a higher cellular uptake in MDA-MB-231 BCE cells than the non-targeted system . Also, the simultaneous delivery of a combination of therapeutic agents has shown higher success in …Author: Piumi Y. Liyanage, Sajini D. Hettiarachchi, Yiqun Zhou, Allal Ouhtit, Elif S. Seven, Cagri Y. Oztan,...

Bacteria-mediated delivery of nanoparticles and cargo into ...

    https://www.nature.com/articles/nnano.2007.149
    Jun 10, 2007 · Bacteria-mediated delivery of nanoparticles and cargo into cells ... These bacteria need specific surface molecules that interact with host ... Other nanoparticle-only based drug delivery ...Author: Demir Akin, Jennifer Sturgis, Kathy Ragheb, Debby Sherman, Kristin Burkholder, J. Paul. Robinson, Ar...

Peptide-MediatedTargeted Drug Delivery

    http://www.biosyn.com/Images/ArticleImages/pdf/Peptide-MediatedTargeted%20Drug%20Delivery.pdf
    Peptide-MediatedTargeted Drug Delivery Sumit Majumdar and Teruna J. Siahaan Department of Pharmaceutical Chemistry, The University of Kansas, Simons Research Laboratories, 2095 Constant Ave., Lawrence, Kansas 66047 DOI 10.1002/med.20225. Abstract: Targeted drug delivery to specific group of cells offers an attractive strategy to minimize the

Surface-kinetics mediated mesoporous multipods for ...

    https://www.nature.com/articles/s41467-019-12378-0
    Sep 26, 2019 · Herein, the surface-kinetics mediated multi-site nucleation strategy is demonstrated for the fabrication of mesoporous multipods with precisely tunable surface topological structures.Author: Tiancong Zhao, Liang Chen, Peiyuan Wang, Benhao Li, Runfeng Lin, Areej Abdulkareem Al-Khalaf, Wael N...

Decorating Nanoparticle Surface for Targeted Drug Delivery ...

    https://www.mdpi.com/2073-4360/8/3/83/htm
    The size, shape, stiffness (composition) and surface properties of nanoparticles (NPs) have been recognized as key design parameters for NP-mediated drug delivery platforms. Among them, the surface functionalization of NPs is of great significance for targeted drug delivery. For instance, targeting moieties are covalently coated on the surface of NPs to improve their selectively and affinity ...Author: Zhiqiang Shen, Mu-Ping Nieh, Ying Li

Drug Releasing Polymer Thin Films: New Era of Surface ...

    https://www.researchgate.net/publication/43347250_Drug_Releasing_Polymer_Thin_Films_New_Era_of_Surface-Mediated_Drug_Delivery
    43 In contrast to systemic particulate drug delivery, surface-mediated drug delivery delivers drugs at the localized treatment site, allowing great spatial control over the release of therapeutic ...Author: Alexander N Zelikin

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