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https://www.ncbi.nlm.nih.gov/pubmed/28752598
Next, we aim to give a brief overview, which provides an emphasis and discussion of recent reports using supercritical carbon dioxide (SC-CO2 ) for fabrication of polymeric carriers, for applications in areas related to drug delivery, tissue engineering, bio-imaging, and other biomedical applications. We finally summarize with perspectives.Author: Ranjith Kumar Kankala, Yu Shrike Zhang, Shi-Bin Wang, Chia-Hung Lee, Ai-Zheng Chen
https://www.sciencedirect.com/journal/advanced-drug-delivery-reviews/vol/60/issue/3
Drug Delivery Applications of Supercritical Fluid Technology. Edited by Y. Kawashima, P. York. Volume 60, Issue 3, ... Drug delivery applications of supercritical fluid technology. Yoshiaki Kawashima, Peter York. Pages 297-298 ... select article Biodegradable particle formation for drug and gene delivery using supercritical fluid and dense gas ...
https://onlinelibrary.wiley.com/doi/full/10.1002/adhm.201700433
The supercritical fluid (SCF) technology is perhaps one of the most renowned high‐pressure techniques so far to obtain products with better performances. ... Drug delivery relies on various formulations and strategies for transporting pharmaceutically active compounds to achieve desired therapeutic effects. 4 However, it has been associated ...Author: Ranjith Kumar Kankala, Yu Shrike Zhang, Shi-Bin Wang, Chia-Hung Lee, Ai-Zheng Chen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849475/
[3,6,16c,17] In general, CO 2 is the most used supercritical solvent and is recognized as safe by the United States Food and Drug Administration (US-FDA) in the pharmaceutical processing, i.e., drug delivery applications, because of its low toxicity, low cohesive energy, as well as low density.
https://www.sciencedirect.com/science/article/pii/S0896844606000362
A new clean and environmentally friendly technique is proposed to prepare molecularly imprinted polymers for controlled drug delivery. In this first attempt to prepare MIPs using supercritical fluid technology a highly cross-linked polymer was prepared and two different templates were tested with successful results.Author: Ana Rita C. Duarte, Teresa Casimiro, Ana Aguiar-Ricardo, Ana Luísa Simplício, Catarina M.M. Duarte
http://www.appliedseparations.com/pharmaceuticals.html
In addition, many drug delivery applications provide increased. benefits compared with conventional techniques. Supercritical CO 2 is the most widely used supercritical fluid in the pharmaceutical industry because it has a low critical temperature (31°C), is non-flammable, non-toxic, inexpensive and is Generally Recognized as Safe (GRAS).
http://www.ijnnonline.net/article_38327_32e789112e86cb79465a3d5d307fbb16.pdf
and inexpensive solvent which has been used for preparation of nanodrugs and nanocarriers in drug delivery system with supercritical fluid technology. Delivery of a drug is one of the most challenging research areas in pharmaceutical sciences. With a combination of drugs and innovative delivery systems
https://www.researchgate.net/publication/229095413_Drug_delivery_goes_supercritical
Many review and research articles have been published on the topic of using supercritical fluid techniques for the development of drug delivery [1] [2][3][4][5][6][7], biomedical and ...
https://pdfs.semanticscholar.org/a5c8/1d1eb1c18ebc8f1b7d2cb1bd7a482893dc2b.pdf
The supercritical fluid impregnation proved to be feasible for the preparation of a new ophthalmic drug delivery system26. 3.1.Particle generation and co-precipitation The various stages of particle formation by supercritical fluid processing can be broadly classified into …
https://www.researchgate.net/publication/311611939_SUPERCRITICAL_FLUID_IMPREGNATION_FOR_THE_ELABORATION_OF_SUSTAINED_RELEASE_DRUG_DELIVERY
Alternatively, DDS may be prepared using supercritical fluid impregnation. This technique has successfully proved its applicability to the preparation of drug delivery systems[4][5] [6] [7][8][9 ...
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