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https://www.nature.com/articles/s41401-019-0287-8
Aug 23, 2019 · A dimerized HIV-1 TAT peptide was used to formulate a nanoparticle vector (dTAT NP) to leverage the efficiency of this cell penetration strategy for tumor-targeted gene delivery . In cell culture ...Author: Hui-hai Zhong, Hui-hai Zhong, Hui-yuan Wang, Jian Li, Yong-zhuo Huang
https://www.researchgate.net/publication/236045202_Needle-free_Gene_Delivery_Through_the_Skin_An_Overview_of_Recent_Strategies
Needle-free Gene Delivery Through the Skin: An Overview of Recent Strategies Article · Literature Review (PDF Available) in Current pharmaceutical design 19(41) · March 2013 with 210 Reads
https://bme.duke.edu/research/drug-gene-delivery
Important areas in this growing field include development of delivery vehicles such as plasmids, nanoparticles, viruses, liposomes, peptide/protein complexes, and biomaterial scaffolds, as well as studies of drug and gene transport, delivery strategies, delivery barriers, and immune response to delivery.
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1381-6128&volume=19&issue=41&spage=7301
Keywords:Gene therapy, topical delivery, transdermal delivery, permeation enhancers, non-viral vectors, transfersomes, niosomes, nanoemulsions, biphasic vesicles, gemini-lipid nanoparticles. Abstract:Topical administration is attractive and non-invasive gene delivery approach. It is simple and allows repeated administration.
https://onlinelibrary.wiley.com/doi/full/10.1002/adtp.201800038
Aug 26, 2018 · But controlled non‐viral gene delivery for musculoskeletal regeneration depends on a multifactorial design in which the choice of gene delivery method, therapeutic gene, and supportive biomaterial play a central role for the success of this strategy.
https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
Non-Viral Delivery Systems in Gene Therapy. ... In this chapter we explain the concept and aim of gene therapy, the different gene delivery systems and therapeutic strategies, how genes are delivered and how they reach the target. ... Gene delivery efficiency seems to …
https://www.amazon.com/Gene-Cell-Therapy-Therapeutic-Mechanisms/dp/1466571993
The Most Comprehensive, State-of-the-Art Book on Using Gene and Cell Therapy in Clinical Medicine. Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Fourth Edition presents extensive background and basic information, state-of-the-art technologies, important achievements, and lingering challenges in the fields of gene and cell ...Author: Nancy Smyth Templeton
https://pubs.acs.org/doi/10.1021/mp400467x
Oct 04, 2013 · A key end goal of gene delivery research is to develop clinically relevant vectors that can be used to combat elusive diseases such as AIDS. Despite promising engineering strategies, efficiency and ultimately gene modulation efficacy of nonviral vectors have been hindered by numerous in vitro and in vivo barriers that have resulted in subviral performance. In this perspective, we concentrate ...
https://searchworks.stanford.edu/view/12267486
From introductory information to state-of-the-art technologies and concepts, the book helps readers understand vector design and construction, delivery systems, therapeutic strategies, gene expression and detection, disease targets, clinical applications and trials, cell-based therapies, novel imaging systems, gene regulation, and regulatory ...
https://www.nature.com/articles/nrd.2018.183
Nov 30, 2018 · The requirement for delivery by injection is currently a limitation for the use of biologic drugs such as antibodies. In this Review, Mitragotri and colleagues discuss advances made in non ...
https://biomaterialsres.biomedcentral.com/articles/10.1186/s40824-019-0156-z
Mar 12, 2019 · Gene delivery systems are essentially necessary for the gene therapy of human genetic diseases. Gene therapy is the unique way that is able to use the adjustable gene to cure any disease. The gene therapy is one of promising therapies for a number of diseases such as inherited disorders, viral infection and cancers. The useful results of gene delivery systems depend open the adjustable ...
https://www.youtube.com/watch?v=0qF5pfnQANo
Oct 18, 2018 · SUCCESSFUL STRATEGIES IN THE DESIGN AND DELIVERY OF A CELL/GENE THERAPY CLINICAL DEVELOPMENT PROGRAM WORKSHOP Sponsored by IQVIA Streamlined, rigorous and effective clinical trials translate to ...
https://www.powershow.com/viewfl/1b3e4f-ZDc1Z/Gene_Delivery_powerpoint_ppt_presentation
Delivery Strategies of siRNA 3 What Is Gene Therapy? At the most basic level, gene therapy can be described as the intracellular delivery of genetic material to generate a therapeutic effect by correcting an existing abnormality or providing cells with a new function. 4
https://academic.oup.com/cardiovascres/article/73/3/453/367211
Targeting the heart with gene therapy-optimized gene delivery methods Oliver J. Müller. Internal Medicine III, University of Heidelberg, Germany ... This review article will give a broad overview of different gene delivery strategies that have been applied in …
https://academic.oup.com/humupd/article/22/5/588/2237824
A literature search was performed using the National Center for Biotechnology Information PubMed database up until March 2016 and relevant keywords were used to obtain information regarding mammalian germ cell-specific toxicity and embryotoxicity of ENPs, possible treatment strategies, as well as the anticipated applications of nanoparticles in gene delivery in germ cells and embryos.
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