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https://www.sciencedirect.com/science/article/pii/S0079670019301704
Stimuli-responsive polymer systems have proven to be the efficient tools to achieve controlled drug release which improves the therapeutic effects and reduces the side effects [15,, , , ].Author: Aitang Zhang, Kenward Jung, Aihua Li, Jingquan Liu, Cyrille Boyer
https://www.sciencedirect.com/science/article/pii/S259023851930044X
Motivated by the necessity of drug safety and efficacy, it follows that the gated materials have been extensively studied, mainly including supramolecular polymers and supramolecular pseudorotaxanes for stimuli-responsive drug delivery, which not only endow the delivery systems with flexible and robust attributes of non-covalent interactions but also meet the urgent need of human healthcare.18, 19, 20Author: Zheng Li, Nan Song, Ying-Wei Yang
https://www.nature.com/articles/nmat3776
Oct 23, 2013 · In this Review, we discuss recent advances in the design of nanoscale stimuli-responsive systems that are able to control drug biodistribution in response to specific stimuli, either exogenous (variations in temperature, magnetic field, ultrasound intensity, light or electric pulses) or endogenous (changes in pH,...Author: Simona Mura, Julien Nicolas, Patrick Couvreur
https://onlinelibrary.wiley.com/doi/10.1002/wnan.1450
Abstract. The ultimate goal of drug delivery is to increase the bioavailability and reduce the toxic side effects of the active pharmaceutical ingredient (API) by releasing them at a specific site of action. In the case of antitumor therapy, association of the therapeutic agent with a carrier system can minimize damage to healthy, nontarget tissues,...Author: Y. Lee, D.H. Thompson
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/stimuli-responsive-materials.html
Azobenzene, o -nitrobenzene, coumarin, and pyrene derivatives are routinely used for devising light-responsive drug delivery vectors. Jiang et al. developed a UV-responsive micelle system with poly (ethylene oxide) (PEO) and poly (methacrylate) which included pyrene sidechains as diblock copolymers.
https://www.sciencedirect.com/book/9780128136898/drug-targeting-and-stimuli-sensitive-drug-delivery-systems
Stimuli-responsive DDSs, also termed self-regulating DDSs, are multifunctional delivery systems designed to carry the drug moiety through the body then to release it at a target tissue and at a specified time. The release of the drug at the site of action is triggered by a stimulus…
https://www.sciencedirect.com/science/article/pii/S0010854518300225
Jun 01, 2018 · Stimuli-responsive drug delivery systems were also constructed from various mechanized silica nanoparticles (MSNPs) that were composed of mesoporous silica nanoparticles (MSNs) surface-functionalized by supramolecular nanovalves based on the host–guest interaction between β-CD and Fc group , , , , , , , , , .Author: Haibin Gu, Shengdong Mu, Guirong Qiu, Xiong Liu, Li Zhang, Yanfei Yuan, Didier Astruc
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201801526
Nov 20, 2018 · Intrinsic stimuli are localized within the tumor microenvironment. Compared with healthy tissues, tumor microenvironments have special characteristics such as lower pH and higher temperature that can be employed for developing internal (e.g., pH, redox, ATP) stimuli‐responsive drug delivery systems.
https://pubs.acs.org/doi/abs/10.1021/acsnano.8b06104
Stimuli-Responsive Nano-Architecture Drug-Delivery Systems to Solid Tumor Micromilieu: Past, Present, and Future Perspectives Hossam S. El-Sawy Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo 63514, EgyptAuthor: Hossam S. El-Sawy, Ahmed M. Al-Abd, Tarek A. Ahmed, Tarek A. Ahmed, Khalid M. El-Say, Khalid M. El-S...
http://www.thno.org/v10p4557.htm
Stimuli-responsive nanocarriers for drug delivery, tumor imaging, therapy and theranostics Peng Mi Department of Radiology, Center for Medical Imaging, and State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, No.17 …
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