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https://www.ncbi.nlm.nih.gov/pubmed/12378965
Recently, there has been a great deal of research activity in the development of stimulus-responsive polymeric hydrogels. These hydrogels are responsive to external or internal stimuli and the response can be observed through abrupt changes in the physical nature of the network. This property can be favorable in many drug delivery applications.Author: K. S. Soppimath, T. M. Aminabhavi, A. M. Dave, S. G. Kumbar, W. E. Rudzinski
https://www.tandfonline.com/doi/abs/10.1081/DDC-120006428
Jul 21, 2014 · These hydrogels are responsive to external or internal stimuli and the response can be observed through abrupt changes in the physical nature of the network. This property can be favorable in many drug delivery applications. The external stimuli can be temperature, pH, ionic strength, ultrasonic sound, electric current, etc.Author: K. S. Soppimath, T. M. Aminabhavi, A. M. Dave, S. G. Kumbar, W. E. Rudzinski
https://www.sciencedirect.com/science/article/pii/S0378517320301411
Responsiveness of drug delivery systems (DDS) against internal and external stimuli attracts wide interest as a mechanism that can provide both site-specific release at the target place and feedback regulated release rate.Author: Carmen Alvarez-Lorenzo, Valerij Y. Grinberg, Tatiana V. Burova, Angel Concheiro
https://www.researchgate.net/publication/11081334_Stimulus-Responsive_Smart_Hydrogels_as_Novel_Drug_Delivery_Systems
Within drug delivery systems, the smart stimulus-sensitive hydrogels such as soil temperature, salinity and pH, produce compounds with a prolonged residual activity between applications ...
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2014.940091
Hydrogels are the three-dimensional network structures obtained from a class of synthetic or. natural polymers which can absorb and retain a significant amount of water. Hydrogels are one. of the most studied classes of polymer-based controlled drug release.Author: Nikhil Sood, Ankur Bhardwaj, Shuchi Mehta, Abhinav Mehta
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993976/
Sep 11, 2008 · Stimuli-sensitive hydrogels: A novel ophthalmic drug delivery system Vinod Singh , S S Bushetti , 1 Raju Appala , 2 Adil Shareef , 1 Syed S Imam , and Mamta Singh Department of Pharmaceutics & Pharmacology, SBS PG Institute of Biomedical Sciences and Research, Dehradun, Uttarakhand, India
https://www.sciencedirect.com/science/article/pii/S1742706119303356
Nanogels can be designed to be stimulus responsive, and react to internal or external stimuli such as pH, temperature, light and redox, thus resulting in the controlled release of loaded drugs. This “smart” targeting ability prevents drug accumulation in non-target...Author: Sakineh Hajebi, Navid Rabiee, Mojtaba Bagherzadeh, Sepideh Ahmadi, Mohammad Rabiee, Hossein Roghani-...
https://www.sciencedirect.com/science/article/pii/S1385894719328268
Diverse applications have been found for responsive hydrogels in drug delivery, catalysis, sensor systems and actuators,. There, two main mechanisms are utilized; the control of accessibility of the porous gel network and the control of the bulk gel volume,,.Author: X. Hu, J. Karnetzke, M. Fassbender, S. Drücker, S. Bettermann, B. Schroeter, B. Schroeter, W. Pauer,...
https://www.sciencedirect.com/science/article/pii/S0032386110001503
Mar 24, 2010 · A novel family of stimuli-responsive smart hydrogel is developed in this study for K +-induced self-regulated controlled-release, which is featured with isothermally K +-induced pulse-release mode at a certain temperature due to the isothermally K +-induced shrinking behavior of the hydrogel by recognizing the increase of K + concentration in the environment.Author: Peng Mi, Xiao-Jie Ju, Rui Xie, Han-Guang Wu, Jiang Ma, Liang-Yin Chu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924501/
Jun 07, 2016 · As a smart drug carrier system, ThermoDox, temperature-sensitive DOX liposomes developed by the company Celsion may be the closest formulation to the clinic so far. ... Stimuli-responsive drug-delivery systems in clinical trials. ... Hu K, Sun J, Guo Z, Wang P, Chen Q, Ma M. et al. A novel magnetic hydrogel with aligned magnetic colloidal ...Author: Dong Liu, Fang Yang, Fei Xiong, Ning Gu
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