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https://www.nature.com/articles/ncomms15678
May 30, 2017 · Conjugation of squalene to gemcitabine as unique approach exploiting endogenous lipoproteins for drug delivery. Nat. Commun. 8, 15678 doi: 10.1038/ncomms15678 (2017).Author: Dunja Sobot, Simona Mura, Semen O. Yesylevskyy, Laura Dalbin, Fanny Cayre, Guillaume Bort, Julie Mou...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254918/
Sep 01, 2009 · Squalene is widely used for numerous vaccine and drug delivery emulsions due to its stability-enhancing effects and biocompatibility. Emulsions containing squalene facilitate solubilization, modified release, and cell uptake of drugs, adjuvants, and vaccines.Author: Christopher B. Fox
https://www.mdpi.com/1420-3049/14/9/3286/htm
Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing emulsions are evaluated in the context of parenteral formulations. Historical and current ...Author: Christopher B. Fox
https://www.ncbi.nlm.nih.gov/pubmed/19783926
Sep 01, 2009 · Squalene emulsions for parenteral vaccine and drug delivery. Fox CB(1). Author information: (1)Infectious Disease Research Institute, Seattle, WA 98104, USA. [email protected] Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery.Author: Christopher B. Fox
https://www.researchgate.net/publication/26840744_Squalene_Emulsions_for_Parenteral_Vaccine_and_Drug_Delivery
Sep 01, 2009 · Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of ...Author: Christopher B Fox
https://www.mdpi.com/1420-3049/14/9/3286/pdf
Abstract: Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented. Moreover, the physicochemical and biological properties of squalene-containing emulsions are evaluated in the context ofAuthor: Christopher B. Fox
https://www.sciencedirect.com/science/article/pii/B9780124160033000147
Squalenoyl nanomedicine is one fine example for squalene-based lipid–drug conjugates. In this technology, squalene's natural folding conformation was used to attach hydrocarbon to analogues of anticancer and antiviral drugs which resulted in formation of nanoassemblies in water with a diameter of 100–300 nm in the absence of any surfactants.Author: Se-Kwon Kim, Fatih Karadeniz
https://en.wikipedia.org/wiki/Squalene
Squalene is a natural organic compound originally obtained for commercial purposes primarily from shark liver oil (hence its name, as Squalus is a genus of sharks), although plant sources (primarily vegetable oils) are now used as well, including amaranth seed, rice bran, wheat germ, and olives. Yeast cells have been genetically engineered to produce commercially useful quantities of ...Boiling point: 285 °C (545 °F; 558 K) at 3.3 kPa
http://skinbio.com/squalene-skin.pdf
Squalene is also used as a material or additive in topically applied vehicles such as lipid emulsions and nanostructured lipid carriers (NLCs). Lipid emulsions Lipid emulsions are potentially interesting drug delivery systems because of their ability to incorporate drugs with poor solubility within the dispersal phase (Figure 3).
https://www.sciencedirect.com/science/article/pii/S1631074818300584
Squalene versus cholesterol: Which is the best nanocarrier for the delivery to cells of the anticancer drug gemcitabine? Squalène ou cholestérol : quel est le meilleur nanovecteur pour la délivrance de l'anticancéreux gemcitabine aux cellules ?Author: Arnaud Peramo, Simona Mura, Semen O Yesylevskyy, Bruno Cardey, Dunja Sobot, Stephanie Denis, Christo...
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