Spinal Drug Delivery Yaksh

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Spinal Drug Delivery. Anesthesiology ASA Publications

    https://anesthesiology.pubs.asahq.org/article.aspx?articleid=1945638
    Spinal Drug Delivery is a deep, sometimes tough, but always efficient, compendium edited by Yaksh et al. Its aim is to describe spinal drug delivery in human therapy. For more than a century, considerable work has been done to deliver medicines (e.g. , local anesthetics and, more recently, numerous other drugs) near the central nervous system and essentially close to the dorsal horn of the ...Author: M. Gentili, Francis Bonnet

Spinal Drug Delivery: 9780444829016: Medicine & Health ...

    https://www.amazon.com/Spinal-Drug-Delivery-T-Yaksh/dp/0444829016
    This book provides a unified and comprehensive compendium of issues related to the spinal delivery of drugs. The text, consisting of 34 chapters, begins with an extensive review of the early history, reflecting the development of the spinal cord as a route of spinal drug delivery.Price: $142.14

Tony Yaksh UCSD Profiles

    https://profiles.ucsd.edu/tony.yaksh
    Bert RJ, Hayek SM, Yaksh TL. Modeling Spinal Intrathecal Drug Distribution: The Challenge of Defining and Predicting Cerebrospinal Fluid Dynamics. Anesth …Occupation: Recall Faculty, Anesthesiology

Tony L. Yaksh, Ph.D. - medschool.ucsd.edu

    https://medschool.ucsd.edu/som/anesthesia/research/basic-science/yaksh-res-lab/faculty/Pages/Yaksh.aspx
    The widespread adoption of the intrathecal route of drug delivery in humans for acute delivery and chronic infusion was largely accomplished in the absence of any systematic assessment of safety. ... Dennis EA, Svensson CI, Corr M, Yaksh TL. Spinal TLR4 mediates the transition to a persistent mechanical hypersensitivity after the resolution of ...

Pain relief through spinal drug delivery system - WebMD

    https://www.webmd.com/pain-management/guide/spinal-drug-delivery-systems
    Spinal drug delivery systems increase pain relief and comfort for people with severe pain with less medicine. In addition, the system can cause fewer side effects than oral medications because ...

Intrathecal Catheterization and Drug Delivery in the Rat ...

    https://link.springer.com/protocol/10.1385%2F1-59259-770-X%3A011
    A primary method in such investigations is the specific delivery of drugs into the spinal intrathecal space to assess such agents with the actions limited to the spinal cord. The rat has served as a primary model in these investigations.Author: Shelle A. Malkmus, Tony L. Yaksh

Spinal Drug Delivery - T L Yaksh - Bok (9780444829016) Bokus

    https://www.bokus.com/bok/9780444829016/spinal-drug-delivery/
    This book provides a unified and comprehensive compendium of issues related to the spinal delivery of drugs. The text, consisting of 34 chapters, begins with an extensive review of the early history, reflecting the development of the spinal cord as a route of spinal drug delivery. It then presents 4 principal divisions. In the first, the embryology, anatomy of the spinal canal, the spinal ...

Toxicology Evaluation of Drugs Administered via Uncommon ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874330/
    Yaksh TL. Spinal delivery and assessment of drug safety. In: Bolon B, Butt MT, editors. Fundamental Neuropathology for Pathologists and Toxicologists: Principles and Techniques. 1. John Wiley & Sons, Inc; 2011. pp. 449–462. [Google Scholar]

Cerebrospinal Fluid and Spinal Cord Distribution of ...

    https://anesthesiology.pubs.asahq.org/article.aspx?articleid=1923122
    Artru A: Spinal cerebrospinal fluid chemistry and physiology, Spinal Drug Delivery. Edited by Yaksh T. Amsterdam, Elsevier, 1999, pp 176–237Artru, A Yaksh T Amsterdam Elsevier. Fig. 1. Photographs of an approximately 3-cm-long section of spinal cord from a single pilot animal in which methylene blue was added to the drug infusion (20 μl/h ...Author: Christopher M. Bernards

The Effects of Intrathecal and Systemic Gabapentin on ...

    https://journals.lww.com/anesthesia-analgesia/Fulltext/2011/04000/The_Effects_of_Intrathecal_and_Systemic_Gabapentin.33.aspx
    Rats were implanted with a single IT catheter for drug delivery. 22, 23 In brief, rats anesthetized with isoflurane in an air/oxygen mixture (1:1) were implanted with a polyethylene (outside diameter 0.36 mm) catheter passed through the cisternal membrane into the IT space to the level of the L2 to 3 spinal segments (approximately 8.5 cm) and ...

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