Spatial Drug Delivery

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Spatial, Temporal, and Dose Control of Drug Delivery using ...

    https://www.ncbi.nlm.nih.gov/pubmed/30633500
    Feb 26, 2019 · Spatial, Temporal, and Dose Control of Drug Delivery using Noninvasive Magnetic Stimulation. Chen W, Cheng CA, Zink JI. Noninvasive stimuli-responsive drug delivery using magnetic fields in conjunction with superparamagnetic nanoparticles offers the potential for the spatial and temporal control of drug release.Author: Wei Chen, Chi-An Cheng, Jeffrey I. Zink

Spatial, Temporal, and Dose Control of Drug Delivery using ...

    https://pubs.acs.org/doi/10.1021/acsnano.8b06655
    Jan 11, 2019 · Noninvasive stimuli-responsive drug delivery using magnetic fields in conjunction with superparamagnetic nanoparticles offers the potential for the spatial and temporal control of drug release. When hyperthermia is not desired and control of the dosage is required, it is necessary to design a platform in which local heating on the nanoscale releases the therapeutic cargo without the bulk ...Author: Wei Chen, Chi-An Cheng, Jeffrey I. Zink

Spatial mapping of drug delivery to brain tissue using ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157604/
    We present an application of spatial frequency-domain imaging (SFDI) to the wide-field imaging of drug delivery to brain tissue. Measurements were compared with values obtained by a previously validated variation of diffuse reflectance spectroscopy, the method of optical pharmacokinetics (OP).Author: Rajinder P. Singh-Moon, Darren M. Roblyer, Irving J. Bigio, Shailendra Joshi

SUSTAINED RELEASE DRUG DELIVERY SYSTEM : A CONCISE …

    https://www.pharmatutor.org/articles/sustained-release-drug-delivery-system-concise-review
    They are distinguished from rate-controlled drug delivery systems, which are able to specify the release rate and duration in vivo precisely, on the basis of simple invitro tests. Drug targeting; on the other hand, can be considered as a form of controlled release in that exercises spatial control of …

Designing hydrogels for controlled drug delivery Nature ...

    https://www.nature.com/articles/natrevmats201671
    Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and …Author: Jianyu Li, David J. Mooney

Spatial characterization of a multifunctional pipette for ...

    https://www.sciencedirect.com/science/article/pii/S0165027014004385
    The latter is the most commonly used method in tissue slice studies, where tissue is soaked in the circulated drug solution in the bath. The spatial drug delivery profile of the MFP was determined with and without HCF by turning the aspiration on and off, respectively. 2.5. Data processingAuthor: Aikeremu Ahemaiti, Holger Wigström, Alar Ainla, Gavin Jeffries, Owe Orwar, Aldo Jesorka, Kent Eric J...

Chemical and spatial analysis of protein loaded PLGA ...

    https://www.sciencedirect.com/science/article/pii/S0168365912003367
    Chemical and spatial analysis of protein loaded PLGA microspheres for drug delivery applications. ... This work represents the first example where the spatial location of the protein, surfactant and the polymer substrate in the ToF-SIMS images of the microparticle surfaces has been demonstrated.Author: A. Rafati, A. Boussahel, K.M. Shakesheff, A.G. Shard, C.J. Roberts, X. Chen, D.J. Scurr, S. Rigby-Si...

Spatial Modeling of Drug Delivery Routes ... - Cancer Research

    https://cancerres.aacrjournals.org/content/76/6/1320
    Mar 15, 2016 · Here, we report results of a 3-dimensional spatial model of drug delivery using OvTM, our ovarian tumor model parameterized for ovarian tumor spheroids in the peritoneum. OvTM was based on the cellular Potts model using the CompuCell3D simulation environment . We extend the OvTM to study drug dynamics for two delivery compartments, the blood ...Author: Kimberly R. Kanigel Winner, Mara P. Steinkamp, Rebecca J. Lee, Maciej Swat, Carolyn Y. Muller, Melan...

Spatial mapping of drug delivery to brain tissue using ...

    http://www.bu.edu/bmo/files/2014/09/Raj_SFDI-drug-delivery_JBO-Sept2014.pdf
    Spatial mapping of drug delivery to brain tissue using hyperspectral spatial frequency-domain imaging Rajinder P. Singh-Moon,a Darren M. Roblyer,b Irving J. Bigio,b,c and Shailendra Joshia,* aColumbia University College of Physicians and Surgeons, Department of Anesthesiology, 630 West 168th Street, New York, New York 10032, United States

(PDF) Spatial drug delivery through hyaluronic acid ...

    https://www.researchgate.net/publication/328980680_Spatial_drug_delivery_through_hyaluronic_acid-paclitaxel_conjugate-loaded_nanoparticles_for_the_effective_treatment_of_solid_tumors
    Spatial drug delivery through hyaluronic acid-paclitaxel conjugate-loaded nanoparticles for the effective treatment of solid tumors

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