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https://pubs.acs.org/doi/10.1021/acsnano.8b06655
Jan 11, 2019 · Noninvasive stimuli-responsive drug delivery using magnetic fields in conjunction with superparamagnetic nanoparticles offers the potential for the spatial and temporal control of drug release.Author: Wei Chen, Chi-An Cheng, Jeffrey I. Zink
https://www.jstage.jst.go.jp/article/dds1986/10/5/10_5_329/_article
Spatial and Temporal Control of Drug Delivery Site-dependent delivery of peptide drugs in the gastrointestinal tract Mariko Morishita 1), Tsuneji Nagai 1) 1) Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Hoshi University Released 2009/02/23 Keywords: insulin, ...
https://www.jstage.jst.go.jp/article/dds1986/10/5/10_5_337/_article
Spatial and Temporal Control of Drug Delivery. Targeting delivery of prostaglandins and other drugs—Basic and clinical study—. Prostaglandin E 1 (PGE 1 ), a vasodilator and platelet aggregation inhibitor, effectively treats many diseases.
https://www.engineering.cornell.edu/drug-delivery-and-nanomedicine
Drug Delivery and Nanomedicine The faculty and students in Cornell biomedical engineering apply engineering principles to design systems that effectively control the spatial and temporal delivery of medicines, to investigate the effects of medicines on cells and tissues, and to evaluate their preclinical and clinical efficacy.
https://www.sciencedirect.com/science/article/pii/S016836591730514X
The drug instability, toxicity and the barrier to the target area necessitate a suitable drug delivery system with an external or internal control of the release. Spatio-temporal control using a surface functionalized nano-carrier seems to be the best alternative for guided drug delivery and release.Author: Nahla Rahoui, Bo Jiang, Nadia Taloub, Yu Dong Huang
http://www.gbv.de/dms/bs/toc/114189854.pdf
Part IV. Drug Carriers and Drug Delivery: Patterning in Time Real Time Response Polymeric Delivery Systems. By ROBERT LANGER and JOSEPH KOST 330 Targetable Polymeric Anticancer Drugs: Temporal Control of Drug Activ-ity. By JINDRICH KOPECEK 335 Pharmacokinetic Aspects of Arterial Fluoropyrimidine Delivery. By JERRY M. COLLINS 345
https://onlinelibrary.wiley.com/doi/10.1002/smll.201903060
Abstract Engineering of smart photoactivated nanomaterials for targeted drug delivery systems (DDS) has recently attracted considerable research interest as light enables precise and accurate controlled release of drug molecules in specific diseased cells and/or tissues in a highly spatial and temporal …Author: Wei Zhao, Wei Zhao, Yongmei Zhao, Qingfu Wang, Tianqing Liu, Jingjiang Sun, Run Zhang
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the …Author: Jianyu Li, David J. Mooney
https://www.sciencedirect.com/science/article/pii/S0168365915002242
Jun 10, 2015 · Spatio-temporal quantification of tumor uptake in orthotopic xenografts was performed using CT at the bulk tissue level, and within defined sub-volumes of the tumor (i.e., rim, periphery and core). Tumor penetration and relative distribution of liposomes were assessed by fluorescence microscopy of whole tumor sections.Author: Sandra N. Ekdawi, James M.P. Stewart, Michael Dunne, Shawn Stapleton, Shawn Stapleton, Nicholas Mits...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2958178/
Drug delivery model. The time and spatially dependent temperature and perfusion resulting from the computational heat-transfer model of RF ablation was used as input data to the drug delivery model. The finite element model (FEM) for drug delivery simulation was created with the FEM-Software Comsol (version 3.5a).Author: Astrid Gasselhuber, Matthew R. Dreher, Ayele Negussie, Bradford J. Wood, Frank Rattay, Dieter Haemme...
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