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https://benthambooks.com/book/9781608051205/
Introduction. This comprehensive ebook covers all the aspects of ADME/PK modeling including solubility, absorption, formulation, metabolic stability, drug-drug interaction potential and a special delivery tool of drug candidates.Author: Karoly Tihanyi, Monika Vastag, O. Balázs, G.T. Balogh, Deli, E. Duda, A.S. Halász, É. Hellinger, K. ...
https://books.google.com/books/about/Solubility_Delivery_and_ADME_Problems_of.html?id=au8XIz98jpUC
Sep 20, 2011 · This comprehensive ebook covers all the aspects of ADME/PK modeling including solubility, absorption, formulation, metabolic stability, drug-drug interaction potential and a special delivery tool of drug candidates. The book provides an integrated view of fundamental ADME issues and challenges in early drug development from the aspect of practicing drug researchers.
http://www.eurekaselect.com/54249/volume/1
Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates This comprehensive ebook covers all the aspects of ADME/PK modeling including solubility, absorption, formulation, metabolic stability, drug-drug interaction potential and a special delivery tool of drug candidates.Author: Karoly Tihanyi, Monika Vastag, O. Balázs, G.T. Balogh, Deli, E. Duda, A.S. Halász, É. Hellinger, K. ...
https://www.overdrive.com/media/1206609/solubility-delivery-and-adme-problems-of-drugs-and-drug-candidates
Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates This comprehensive ebook covers all the aspects of ADME/PK modeling including solubility, absorption, formulation, metabolic stability, drug-drug interaction potential and a special delivery tool of drug candidates.
https://www.worldcat.org/title/solubility-delivery-and-adme-problems-of-drugs-and-drug-candidates/oclc/779141432
Get this from a library! Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates.. [Karoly Tihanyi; Monika Vastag] -- This comprehensive ebook covers all the aspects of ADME/PK modeling including solubility, absorption, formulation, metabolic stability, drug-drug interaction potential and a special delivery tool of ...
http://www.eurekaselect.com/54249
Drug Design, Discovery and Therapy; Earth and Environmental Sciences; Energy and Fuels; Engineering and Technology; Food Sciences and Nutrition; Genetics; Healthcare; Life Sciences; Material Sciences; Medicine; Mathematics and Statistics; Nanoscience; Physics and Astronomy; Social Sciences; Technology Transfer and Entrepreneurship; Exhibit ...
https://www.researchgate.net/publication/280919825_Drug_Transport_and_the_Blood-Brain_Barrier
Drug Transport and the Blood-Brain Barrier Solubility, Delivery and ADME Problems of Drugs and Drug Candidates 159 and Cereport (Table 5 ). If these prove to be a safer a nd more cont rollable way ...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/adme
The ADME properties of drugs and drug candidates can be altered through chemical modifications (Figure 3.1), that is, by introducing new chemical moieties in biologically active compounds (i.e., through prodrug design) or introduction of chemically labile bonds in biologically active compounds (i.e., through soft drug design).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629443/
Aug 24, 2015 · Majority of the failures in new drug development have been attributed to poor water solubility of the drug. Issues associated with poor solubility can lead to low bioavailability resulting in suboptimal drug delivery. About 40% of drugs with market approval and nearly 90% of molecules in the discovery pipeline are poorly water-soluble.Author: Sandeep Kalepu, Vijaykumar Nekkanti
https://www.worldcat.org/title/solubility-delivery-and-adme-problems-of-drugs-and-drug-candidates/oclc/769188494
Get this from a library! Solubility, delivery and ADME problems of drugs and drug candidates. [K Tihanyi; M Vastag;]
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