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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4493518/
Jun 08, 2015 · Solid lipid nanoparticles containing MTA have been shown to have higher therapeutic efficacy at low doses with more prolonged effects than those of the drug solution itself [11]. Lipid nanoparticles have also been shown to be feasible for the ocular delivery of anti-inflammatory drugs …Author: Yuhong Wang, Ammaji Rajala, Raju V. S. Rajala
https://www.sciencedirect.com/science/article/pii/B9780128136874000074
Lipid Nanoparticles for Ocular Delivery Lipid nanoparticle suspensions are mainly conceived for topical administration, and consequently for the anterior segment of the eye.Author: Luigi Battaglia, Marina Gallarate, Loredana Serpe, Federica Foglietta, Elisabetta Muntoni, Ana del P...
https://www.ncbi.nlm.nih.gov/pubmed/20491540
Solid lipid nanoparticles (SLNs) have been looked at as a potential drug carrier system since the 1990s. SLNs do not show biotoxicity as they are prepared from physiological lipids. SLNs are especially useful in ocular drug delivery as they can enhance the corneal absorption of drugs and improve the ocular bioavailability of both hydrophilic and lipophilic drugs.Author: Ali Seyfoddin, John Shaw, Raida Al-Kassas
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2010.483257
Solid lipid nanoparticles for ocular drug delivery Ali Seyfoddin, John Shaw, and Raida Al-Kassas University of Auckland, Faculty of Medical and Health Sciences, School of Pharmacy, Auckland, New Zealand Abstract Ocular drug delivery remains challenging because …
https://www.researchgate.net/publication/44619818_Solid_lipid_nanoparticles_for_ocular_drug_delivery
Nanotechnology is expected to revolutionize ocular drug delivery. Many nano-structured systems have been employed for ocular drug delivery and yielded some promising results. Solid lipid nanoparticles (SLNs) have been looked at as a potential drug carrier system since the 1990s.
https://www.sciencedirect.com/science/article/pii/S0378517302000807
Abstract Aim of this study was to evaluate solid lipid nanoparticles (SLN) as carriers for topical ocular delivery of tobramycin (TOB). The SLN were in the colloidal size range (average diameter below 100 nm; polydispersity index below 0.2) and contained 2.5% TOB as ion-pair complex with hexadecyl phosphate.Author: Roberta Cavalli, M.Rosa Gasco, Patrizia Chetoni, Susi Burgalassi, M.Fabrizio Saettone
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693026/
Jun 18, 2013 · Kalam MA, Sultana Y, Ali A, Aqil M, Mishra AK, Chuttani K. Preparation, characterization, and evaluation of gatifloxacin loaded solid lipid nanoparticles as colloidal ocular drug delivery system. J Drug Target.Author: Hong-Yan Zhou, Ji-Long Hao, Shuang Wang, Yu Zheng, Wen-Song Zhang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601815/
Apr 08, 2012 · The goal of this study was to develop and characterize indomethacin-loaded solid lipid nanoparticles (IN-SLNs; 0.1% w/v) for ocular delivery. Methods Various lipids, homogenization pressures/cycles, Tween 80 fraction in the mixture of surfactants (Poloxamer 188 and Tween 80; total surfactant concentration at 1% w/v), and pH were investigated in the preparation of the IN-SLNs.Author: Ketan Hippalgaonkar, Goutham R. Adelli, Kanchan Hippalgaonkar, Michael A. Repka, Soumyajit Majumdar
https://www.sciencedirect.com/science/article/pii/S0378517317308724
A. Seyfoddin, R. Al-KassasDevelopment of solid lipid nanoparticles and nanostructured lipid carriers for improving ocular delivery of acyclovir Drug Dev. Ind. Pharm., 39 (2013), pp. 508-519, 10.3109/03639045.2012.665460Author: Jesus Alvarez-Trabado, Jesus Alvarez-Trabado, Yolanda Diebold, Yolanda Diebold, Alejandro Sanchez
https://www.sciencedirect.com/science/article/pii/S1773224719311396
Solid lipid nanoparticle (SLN) represents an excellent option for ocular delivery for properties such as higher stability, non-toxicity, biocompatibility and also has lipid composition similar to physiological lipids . Hence, Bimatoprost encapsulated within the SLN formulation may reduce the frequent complaints of pigmentation along with other side-effects.Author: Rita N. Wadetwar, Ashish R. Agrawal, Pranita S. Kanojiya
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