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https://www.ncbi.nlm.nih.gov/pubmed/12149954/
Dried sodium alginate beads reswell, creating a diffusion barrier decreasing the migration of small molecules (e.g., drugs). The ability of alginate to form two types of gel dependent on pH, i.e., an acid gel and an ionotropic gel, gives the polymer unique properties compared to neutral macromolecules.Author: Hanne Hjorth Tønnesen, Jan Karlsen
https://www.sciencedirect.com/science/article/pii/B9780128170557000030
Sodium alginate is one of the most widely used natural polymers in the field of drug delivery and biomedical applications. It is a cheap, easily available, biocompatible, biodegradable, and nontoxic polysaccharide having innumerable applications in the pharmaceutical as well as food industry.Author: Kiran Chaturvedi, Kuntal Ganguly, Uttam A. More, Kakarla Raghava Reddy, Tanavi Dugge, Balaram Naik, ...
https://www.tandfonline.com/doi/pdf/10.1081/DDC-120003853
sodium alginate beads reswell, creating a diffusion barrier decreasing the migra-. tion of small molecules (e.g., drugs). The ability of alginate to form two types of. gel dependent on pH, i.e., an acid gel and an ionotropic gel, gives the polymer. unique properties compared to neutral macromolecules.
https://www.ukessays.com/essays/biology/sodium-alginate-and-polymer-drug-delivery-systems-biology-essay.php
In recent years a lrge number of biodegradable polymers have been investigated for their potential use as drug delivery systems. among them, sodium alginate and chitosan are very promising and have been widely exploited in pharmaceutical industry for sustained drug release. polysaccharides such as alginic acid, agar, chitin and chitosan have been used to agglomerate drugs for controlled drug delivery …
https://pharmahub.org/resources/534/download/Alginate_Bead_Experiment.pdf
alginate our hydrogels, the chains are connected by calcium ions. There are “spaces” between crosslinks (designated by the symbol ζ in Figure 4) that allow for drug diffusion. Smaller molecules can diffuse through these spaces more easily, resulting in increased drug delivery rates. Figure 3. Solute diffusing through a spherical hydrogel. Figure 4.File Size: 165KB
https://www.sciencedirect.com/science/article/pii/S1773224719312377
In this study, an optimal combination of sodium alginate (SA)/polyvinyl alcohol (PVA) hydrogel containing Rosuvastatin-loaded chitosan (CS) nanoparticles was fabricated as the drug delivery system (DDS). First, the drug-loaded nanoparticles were synthesized by the ionic gelation method.Author: M. Afshar, G. Dini, S. Vaezifar, M. Mehdikhani, B. Movahedi
https://www.researchgate.net/publication/40773276_Sodium_alginate_The_wonder_polymer_for_controlled_drug_delivery
The sodium alginate is a versatile functional biomaterial for viscosity enhancement, stabilizer, matrixing agent, encapsulation polymer, bioadhesive and film former in …
https://www.researchgate.net/publication/11232706_Alginate_in_Drug_Delivery_Systems
Bioadhesive tablets for intraoral drug delivery were prepared by directly compressing the drug with a mixture of chitosan and sodium alginate in weight ratios of 4:1, 1:1 and 1:4, and the adhesion and release characteristics of the prepared systems were evaluated in vitro and in vivo.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178974/
Montmorillonite-Alginate Composites as a Drug delivery System: Intercalation and In vitro Release of Diclofenac sodium B. D. Kevadiya , H. A. Patel , G. V. Joshi , S. H. R. Abdi , and H. C. Bajaj * Discipline of Inorganic Materials and Catalysis, Central Salt and Marine Chemicals Research Institute, Council of Scientific and Industrial Research ...
https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-alginate
Salts and esters of ALGINIC ACID that are used as HYDROGELS; DENTAL IMPRESSION MATERIALS, and as absorbent materials for surgical dressings (BANDAGES, HYDROCOLLOID). They are also used to manufacture MICROSPHERES and NANOPARTICLES for DIAGNOSTIC REAGENT KITS and DRUG DELIVERY SYSTEMS.
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