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https://www.urtech.ca/2011/12/solved-4-2-1-unable-to-connect-attempted-failover-to-alternate-host/
Dec 21, 2011 · 451 4.4.0 Primary target IP address responded with: “421 4.2.1 Unable to connect.” Attempted failover to alternate host, but that did not succeed. Either there are no alternate hosts, or delivery failed to all alternate hosts. Below are the three items you need to check: Test the connection by sending an email through command line.
https://practical365.com/exchange-server/messages-queuing-error-451-4-4-0-dns-query-failed/
Oct 16, 2014 · Thank you for this… We just started experiencing this with accounts that we migrated from our on-premise Exchange 2010/Server 2008 environment to Office365, where we are routing our mail first through our on-premise server and then to O365.
https://social.technet.microsoft.com/Forums/exchange/en-US/36d00792-efcb-49d3-a9a0-69d6a36a4ab2/451-440-primary-target-ip-address-responded-with-quot421-421-unable-to-connectquot
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http://forums.msexchange.org/m_1800438835/tm.htm
Nov 27, 2007 · 451 Primary target ip address responded with: 421 4.2.1 Unable to connect. Attempted failover to alternate host., but that did not suceed. Either there are no alternate hosts, or delivery failed to all alternate hosts. I have move DC from server A to server B and demmoted server A. I have also moved DNS from server A to B.
https://community.spiceworks.com/topic/950432-exchange-2013-unable-to-send-mail-externally
May 18, 2015 · Got the new exchange 2013 server setup without any dramas. However while currently testing, I'm unable to send mail outside the organisation. The setup is Exchange 2013 on Server 2012.
https://docs.microsoft.com/en-us/Exchange/mail-flow/queues/queues
Queues and messages in queues in Exchange Server. 2/8/2020; 26 minutes to read +2; In this article. A queue is a temporary holding location for messages that are waiting to enter the next stage of processing or delivery to a destination. Each queue represents a logical set of messages that the Exchange server processes in a specific order.
https://www.petri.com/forums/topic/no-outgoing-mail-on-my-exchange-2010-server
May 06, 2011 · Re: No outgoing mail on my Exchange 2010 server. Yes I can confirm that XWall listens on port 25. Incoming mail is working fine and when I check on MXToolbox.com it displays 220 mail.xxx.com ESMTP ...
https://answers.microsoft.com/en-us/windows/forum/windows_7-ecoms/unable-to-connect-to-email-server/f1e3f113-afd0-45ba-abda-19f1d1d1b8e0
Apr 07, 2020 · Tech support scams are an industry-wide issue where scammers trick you into paying for unnecessary technical support services. You can help protect yourself from scammers by verifying that the contact is a Microsoft Agent or Microsoft Employee and that the phone number is an official Microsoft global customer service number.
http://forums.msexchange.org/m_1800438835/printable.htm
"451 4.4.0 Primary target Ip address... 4.2.1 unable to connect" (11.May2007 10:33:28 AM) I get the same thing when I disconnect the network cable from a CAS/HUB server. This would lead me to believe it cannot communicate with the intended server and may be a DNS issue.
https://communities.vmware.com/thread/466932
Jan 01, 2014 · Re: Unable to connect to connection server pengwang Jan 1, 2014 7:44 PM ( in response to Rajeev S ) Firstly please check whether Internet Explorer in your client host to use a proxy, if yes, please make sure the proxy can connect to View server, or …
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