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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924501/
Jun 07, 2016 · The design and fabrication of nanoparticles responsive to Glutathione (GSH) can be a promising approach for targeting drug delivery 33. The GSH reduction is a well-known redox system within cancer cells. On one hand, concentrations of GSH in blood and normal extracellular matrices are reported to be 2-20 μM,...Author: Dong Liu, Fang Yang, Fei Xiong, Ning Gu
https://www.intechopen.com/books/smart-drug-delivery-system
From their direct and recent experience, the readers can achieve a wide vision on the new and ongoing potentialities of different smart drug delivery systems. Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery.Author: Ali Demir Sezer
https://www.insidescience.org/video/smart-drug-delivery-system
Apr 22, 2014 · Now scientists at Texas A&M University in College Station have discovered a new method that could change drug delivery. It’s what biomedical engineer Mike McShane calls a “smart” material. “Smart materials are materials that respond to their environment,” said McShane. The material is a gel that contains dye and microcapsules.
http://www.thno.org/v06p1306.htm
The Smart Drug Delivery System and Its Clinical Potential Dong Liu, Fang Yang , Fei Xiong, Ning Gu State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biomedical Sciences and Medical Engineering, Southeast University, Nanjing, 210009, China.
https://pubs.rsc.org/en/content/articlelanding/2014/cc/c4cc01429d
Smart drug delivery systems: from fundamentals to the clinic ... their properties as a function of the intensity of the signal and that enable the transduction into changes in the delivery system that affect its ability to host/release a therapeutic substance. Integration of responsive materials into implantable depots, targetable nanocarriers ...Author: Carmen Alvarez-Lorenzo, Angel Concheiro
http://pubs.acs.org/doi/abs/10.1021/bc060080h
To develop targeted pharmaceutical carriers additionally capable of responding to certain local stimuli, such as decreased pH values in tumors or infarcts, targeted long-circulating PEGylated liposomes and PEG-phosphatidylethanolamine (PEG-PE)-based micelles have been prepared with several functions. First, they are capable of targeting a specific cell or organ by attaching the monoclonal ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108334/
Aug 20, 2018 · NP drug-delivery systems that can release the drug in response to specific physiological triggers, at the appropriate time, and at the correct target site are referred to as smart NPs.11 For this review, smart NPs refer to those incorporating all three delivery strategies: passive, active, and stimuli-responsive targeting,6 as summarized in Figure 1.Author: Regina-Veronicka Kalaydina, Komal Bajwa, Bessi Qorri, Alexandria Decarlo, Myron R Szewczuk
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in the near future.
https://www.westpharma.com/products/self-injection-platforms/smartdose
The SmartDose platform offers a wearable, subcutaneous injector with an integrated drug delivery system that incorporates human factors and usability testing to deliver a truly patient-centric approach to self-administration.
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