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https://www.researchgate.net/publication/270275859_Sustained_Release_Drug_Delivery_Systems_A_Patent_Overview
Sustained Release Drug Delivery System (SRDDS) is designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time with minimum side effects.
https://www.novalaka.com/
NovaLaka is a technological innovator of slow release drug delivery systems in the drug delivery market focused on the trans-mucosal route and specialising in female healthcare. The idea behind the technology arose from the glaucoma research supervised by NovaLaka's cofounders at the Jerusalem College of Engineering in Israel.
https://www.pharmatutor.org/articles/sustained-release-drug-delivery-system-concise-review
The basic rationale of sustained release drug delivery system optimizes the biopharmaceutical, pharmacokinetic and pharmacodynamics properties of a drug in such a way that its utility is maximized, side-effects are reduced and cure of the disease is achieved.
https://www.imedpub.com/articles/oral-sustained-release-tablets-an-overview-with-a-special-emphasis-on-matrix-tablet.php?aid=19258
Sustained and controlled drug delivery system helps in maintaince of constant plasma drug concentration and retards the release rate of drug therby extending the duration of action. There are various formulation strategies for sustained release tablets among which matrix tablet serves as an important tool.
https://pdfs.semanticscholar.org/2079/b751e16d7a9d34d2e0604a35a312d5bca4b2.pdf
The terms sustained release and controlled release refer to two different types of drug delivery systems, although they are often used interchangeably. Sustained-release dosage forms are systems that prolong the duration of the action by slowing the release of the drug, usually at the cost of delayed
https://www.researchgate.net/publication/286148457_Sustained_release_drug_delivery_system_potential
Sustained release dosage forms afford a less dosage frequency, a better control of plasma drug levels, less side effects, increased efficacy and persistent delivery [11]. In controlled release systems therapeutic agents' maybe automatically delivered at predetermined rates over a stretched period of time [12]. ...
https://www.sciencedirect.com/science/article/pii/S0168365920302108
Apr 02, 2020 · Slow release systems are promising to optimize CTLA-4 therapy. Injectable hydrogels were tested for slow release of anti-CTLA-4 antibody. Hydrogels were biocompatible and reduced systemic antibody levels. Hydrogel based CTLA-4 therapy effectively inhibited tumor growth.
https://en.wikipedia.org/wiki/Osmotic_controlled-release_oral_delivery_system
The osmotic-controlled release oral delivery system is an advanced controlled release oral drug delivery system in the form of a rigid tablet with a semi-permeable outer membrane and one or more small laser drilled holes in it. As the tablet passes through the body, water is absorbed through the semipermeable membrane via osmosis, and the resulting osmotic pressure is used to push the active drug through …
https://www.pharmatutor.org/articles/review-sustained-release-dosage-forms
Sustained release concept: - Sustained release, sustained action, prolong action, controlled release, extended action, depot are terms used to identify drug delivery systems that are designed to achieve prolong therapeutic effect by continuously releasing medication over an extended period of time after administration of single dose. In the case of orally administer this period is measured in hours while in …
https://ptfarm.pl/pub/File/Acta_Poloniae/2010/3/217.pdf
patterns can be divided into those that release drug at a slow zero or first order rate and those that pro-vide an initial rapid dose, followed by slow zero or first order release of sustained component (1). The purpose of the controlled release systems is to main-tain drug concentration in the blood or in target tis-
https://www.slideshare.net/bharathpharmacist/liquid-sustained-release-systems-39686020
Sep 30, 2014 · Decreasing the frequency of dosing. Providing uniform drug delivery. 12 13. SRF’s describes the slow release of a drug substance from a dosage form to maintain therapeutic response for extended period (8-12hrs)of time. Time depends on the dosage form. In oral form it is in hours, and in parenterals it is in days and months.
https://www.pharmpress.com/files/docs/FT_Pharmaceutics_Drug_Delivery_sample.pdf
chapter 1 Controllingdrugdelivery Overview In this chapter we will: & differentiate drug delivery systems according to their physical state & differentiate drug delivery systems according to their route of administration & differentiate drug delivery systems according to their type of drug release & discuss drug transport across epithelial barriers. ...
http://iptonline.com/articles/public/IPTTWELVE80NoPrint.pdf
the case, drug release rates in vivo from most drug delivery systems change as the tablet transits from the Figure 4. DCV mathematical modelling and experimental profi le. acidic stomach to the neutral intestinal environment. In the DCV system, this can be easily adjusted for by the addition of suitable buffers to the formulation.
http://retinatoday.com/2010/06/sustained--release-corticosteroid-delivery-systems
The Verisome delivery system (Icon Biosciences, Inc.; Figure 4) is a sustained-release drug delivery system that can be injected into the eye as a liquid via a standard 30-gauge needle. When injected into the vitreous, the liquid coalesces into a single spherule.
http://www.kinampark.com/T-DrugDel/files/9.%20Mechanisms%20of%20Controlled%20Release.pdf
The drug-release kinetics from each bead is controlled by the thickness of the wax layer. Since the wax layers vary in thickness, the drug delivery from the beads is sustained, and the Spansule® system was designed to sustain drug release for about 12 h. The first drug used in the system was dextroamphetamine sulfate (Dexedrine®), which is ...
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