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https://www.sciencedirect.com/science/article/pii/S0169409X03002436
Electroporation is the transitory structural perturbation of lipid bilayer membranes due to the application of high voltage pulses. Its application to the skin has been shown to increase transdermal drug delivery by several orders of magnitude.Author: Anne-Rose Denet, Rita Vanbever, Véronique Préat
https://www.researchgate.net/publication/290802375_Skin_Electroporation_for_Transdermal_and_Topical_Drug_Delivery
Request PDF Skin Electroporation for Transdermal and Topical Drug Delivery Transdermal drug delivery has the potential to be a non-invasive, convenient and safe method of delivering drugs at ...
https://www.ncbi.nlm.nih.gov/pubmed/15019751
Mar 27, 2004 · Electroporation is the transitory structural perturbation of lipid bilayer membranes due to the application of high voltage pulses. Its application to the skin has been shown to increase transdermal drug delivery by several orders of magnitude.Author: Anne-Rose Denet, Rita Vanbever, Véronique Préat
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal delivery represents an attractive alternative to oral delivery of drugs and is poised to provide an alternative to hypodermic injection too 1 – 4.For thousands of years, people have placed substances on the skin for therapeutic effects and, in the modern era, a variety of topical formulations have been developed to treat local indications.Author: Mark R Prausnitz, Robert Langer
https://link.springer.com/chapter/10.1007/978-3-662-53273-7_7
May 05, 2017 · This chapter presents the mechanism of percutaneous penetration enhancement induced by electroporation, discusses factors influencing percutaneous penetration of drug molecules, addresses effects of electroporation on the skin when used in vivo, and describes the potential use of electroporation for transdermal drug delivery.Author: Babu M. Medi, Buddhadev Layek, Jagdish Singh
https://www.sciencedirect.com/science/article/pii/S1461534700002959
The worldwide transdermal market is currently worth US$2 billion and represents the most successful non-oral systemic drug delivery system. Perhaps more remarkable is the fact that this market is dispersed amongst only eight FDA-approved active agents: scopolamine, nitroglycerin, clonidine, oestradiol, fentanyl, nicotine, testosterone and norethisterone (the latter has been recently approved ...Author: Aarti Naik, Yogeshvar N. Kalia, Richard H. Guy
https://clinicalgate.com/topical-and-transdermal-drug-delivery/
Aug 02, 2015 · • Topical drug delivery treats a local disorder and aims to retain the active pharmaceutical ingredient within the skin. • Transdermal drug delivery the skin to deliver the drug to the systemic circulation. • Skin is a complex multi-layered membrane but the outermost layer, the stratum corneum, provides the principal barrier to drug delivery.
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