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https://www.researchgate.net/publication/6748215_siRNA_Drug_Delivery_by_Biodegradable_Polymeric_Nanoparticles
Request PDF siRNA Drug Delivery by Biodegradable Polymeric Nanoparticles RNA interference (RNAi) is an emerging technology in which the introduction of double-stranded RNA (dsRNA) into a ...
https://www.ingentaconnect.com/content/asp/jnn/2006/00000006/F0020009/art00021
However, the drug delivery of siRNA oligos is very novel and is in great need of future research. To this end, a biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanoparticle drug carrier system was prepared to load siRNA oligos with desired physicochemical properties. The nanoparticles were characterized by scanning electron microscopy and laser diffraction particle sizer.
https://www.sciencedirect.com/science/article/pii/S0927776509004111
Encapsulation of diabetes drugs (insulin) on PCL nanoparticles. Nanoparticles prepared with a blend of a biodegradable polyester PCL and a poly cationic non-biodegradable acrylic polymer have been used as a drug carrier for oral administration of insulin [26]. The rate of …Author: Avnesh Kumari, Sudesh Kumar Yadav, Subhash Chandra Yadav
https://works.bepress.com/matthew-he/41/
However, the drug delivery of siRNA oligos is very novel and is in great need of future research. To this end, a biodegradable poly(D,L-lactide-co-glycolide) (PLGA) nanoparticle drug carrier system was prepared to load siRNA oligos with desired physicochemical properties.Author: Xudong Yuan, Ling Li, Appu Rathinavelu, Jinsong Hao, Madhusudhanan Narasimhan, Matthew He, Viviene H...
https://www.sciencedirect.com/science/article/pii/S0378517317302880
Gene therapy through the use of siRNA and a polymeric carrier are becoming an efficient therapeutic option to conventional pharmaceutical formulations for the treatment of deadly diseases, such as cancer, pulmonary, ocular and neurodegenerative diseases.Author: Gennara Cavallaro, Carla Sardo, Emanuela Fabiola Craparo, Barbara Porsio, Gaetano Giammona
https://www.sciencedirect.com/science/article/pii/S0378517317305604
Polymeric nanoparticles: Promising platform for drug delivery. ... M.M. AmijiDevelopment of novel biodegradable polymeric nanoparticles-in-microsphere formulation for local plasmid DNA ... W. Daear, R. Lobenberg, E.J. PrennerOverview of the preparation of organic polymeric nanoparticles for drug delivery based on gelatine, chitosan, poly(d,l ...Author: Khalid M. El-Say, Khalid M. El-Say, Hossam S. El-Sawy
https://www.precisionnanosystems.com/resource-center/publications/detail/a-novel-biodegradable-system-based-on-poly(lactic-co-glycolic-acid)-nanoparticles-for-delivery-of-a-novel-anticancer-peptide
The successful development of better physicochemical properties for the CK-10 loaded PLGA nanoparticles can improve the RAN blocking by CK-10. A Novel Biodegradable System Based on Poly(lactic-co-glycolic acid) Nanoparticles for Delivery of a Novel Anticancer Peptide
https://www.mdpi.com/2079-4991/10/4/720/pdf
However, their bioavailability in ocular tissues is very low (less than 5%). Therefore, drug delivery systems such as biodegradable polymeric PLGA nanoparticles constitute a suitable alternative to topical eye administration, as they can improve ocular bioavailability and simultaneously reduce drug induced side effects.
https://www.sciencedirect.com/science/article/pii/S1818087614000646
Polymer-mediated anti-cancer siRNA delivery systems Polymer-mediated delivery systems, usually called polymeric nanoparticles, are solid, biodegradable, colloidal systems which have been widely studied as drug vesicles.Author: Cong-fei Xu, Jun Wang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238292/
Nov 28, 2011 · Biodegradable nanoparticles (NPs) are gaining increased attention for their ability to serve as a viable carrier for site specific delivery of vaccines, genes, drugs and other biomolecules in the body. They offer enhanced biocompatibility, superior drug/vaccine ...Author: Anil Mahapatro, Dinesh K Singh
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