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https://www.researchgate.net/publication/225325139_Silicon_Microneedle_array_with_Biodegradable_Tips_for_Transdermal_drug_delivery
The porous silicon microneedle tips can greatly enhance the transdermal drug delivery in a minimum invasion, ... [Show full abstract] painless, and convenient manner, at the same time; they are ...
https://link.springer.com/article/10.1007/s00542-007-0530-y
Jan 08, 2008 · This paper presents the fabrication process, characterization results and basic functionality of silicon microneedle array with biodegradable tips for transdermal drug delivery. In order to avoid the main problems related to silicon microneedles; the breaking of the top part of the needles inside the skin, a simple solution can be the fabrication of microneedle array with biodegradable tips…Author: Bangtao Chen, Jiashen Wei, Francis E. H. Tay, Yee Ting Wong, Ciprian Iliescu
https://www.researchgate.net/publication/252739896_Microneedles_array_with_biodegradable_tips_for_transdermal_drug_delivery
The porous silicon microneedle tips can greatly enhance the transdermal drug delivery in a minimum invasion, painless, and convenient manner, at the same time; they are breakable and biodegradable.
https://ui.adsabs.harvard.edu/abs/2008arXiv0802.3068C/abstract
In order to avoid the main problems related to silicon microneedles : broking of the top part of the needles inside the skin, a simple solution can be fabrication of microneedles array with biodegradable tips. The silicon microneedles array was fabricated by using reactive ion etching while the biodegradable tips were performed using and anodization process that generates selectively porous silicon …
https://arxiv.org/abs/0802.3068
Abstract: This paper presents the fabrication process, characterization results and basic functionality of silicon microneedles array with biodegradable tips. In order to avoid the main problems related to silicon microneedles : broking of the top part of the needles inside the skin, a simple solution can be fabrication of microneedles array with biodegradable tips.Author: B. Chen, J. Wei, Francis Tay, Y. T. Wong, C. Iliescu
https://www.spiedigitallibrary.org/conference-proceedings-of-spie/7270/1/Microneedles-array-with-biodegradable-tips-for-transdermal-drug-delivery/10.1117/12.810692.full
Dec 30, 2008 · The microneedles array was fabricated by using deep reactive ion etching (DRIE) and the biodegradable tips were made to be porous by electrochemical etching process. The porous silicon microneedle tips can greatly enhance the transdermal drug delivery in a minimum invasion, painless, and convenient manner, at the same time; they are breakable and biodegradable.Author: Ciprian Iliescu, Bangtao Chen, Jiashen Wei, Francis E. H. Tay
https://iopscience.iop.org/article/10.1088/1742-6596/34/1/186
This paper presents developed processes for silicon microneedle arrays microfabrication. Three types of microneedles structures were achieved by isotropic etching in inductively coupled plasma (ICP) using SF 6 /O 2 gases, combination of isotropic etching with deep etching, and wet etching, respectively. A microneedle array with biodegradable porous tips was further developed based on the ...Author: Jing Ji, Francis Eh Tay, Jianmin Miao, Ciprian Iliescu
https://arxiv.org/pdf/0802.3068
Silicon microneedles array with biodegradable tips for transdermal drug delivery penetration into the skin, the microneedles should have a high aspect ratio. The fabrication of the microneedles was realized using an optimized SF6/O2 RIE process. By controlling the two gas flow rate, the microneedles wereAuthor: B. Chen, J. Wei, Francis Tay, Y. T. Wong, C. Iliescu
https://www.sciencedirect.com/science/article/pii/S0168365905000568
To overcome the skin's barrier properties that block transdermal delivery of most drugs, arrays of microscopic needles have been microfabricated primarily out of silicon or metal. This study addresses microneedles made of biocompatible and biodegradable polymers, which are expected to improve safety and manufacturability.Author: Jung-Hwan Park, Mark G. Allen, Mark R. Prausnitz, Mark R. Prausnitz
https://www.sciencedirect.com/science/article/pii/S0927796X16300213
It has been demonstrated that microneedle arrays can increase the number of compounds amenable to transdermal delivery by penetrating the skin's protective barrier, the stratum corneum, and creating a pathway for drug permeation to the dermal tissue below. Microneedles have been extensively investigated in recent decades for drug and vaccine delivery as well as minimally invasive patient …Author: Eneko Larrañeta, Rebecca E.M. Lutton, A. David Woolfson, Ryan F. Donnelly
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