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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522861/
Drug delivery. Porous silica based materials for drug delivery applications emerged in the late 1990's with reports of silica nanopore membranes; one major advantage of the PSi materials is that they can be tailored for continuous or triggered drug release depending on the application. The paracellular delivery of insulin across an intestinal Caco-2 cell monolayer using micro fabricated PSi particles was one of the first examples of drug delivery …
https://www.sciencedirect.com/science/article/pii/B9780128140338000114
Mesoporous Silica Drug-Delivery Systems for Penicillin Antibiotics Penicillin is a group of β-lactam antibiotics still widely in use, even though many bacteria have developed resistance. Penicillin antibiotics are among the first medications effective against bacterial infections caused by …Author: Raul-Augustin Mitran, Mihaela Deaconu, Cristian Matei, Daniela Berger
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943960/
Dec 25, 2017 · This manuscript reviews the recent progress on mesoporous silica nanoparticles as drug delivery systems. Their intrinsic structural, textural and chemical features permit to design versatile multifunctional nanosystems with the capability to target the diseased tissue and release the cargo on demand upon exposition to internal or external stimuli.Author: María Vallet-Regí, Montserrat Colilla, Isabel Izquierdo-Barba, Miguel Manzano
https://grace.com/pharma-and-biotech/en-us/formulation-excipients
SILSOL ® Silica for Drug Delivery Systems SILSOL ® silica was engineered to bring together advanced silica technologies with challenging active pharmaceutical ingredients to help more effectively formulate large class of poorly soluble but otherwise promising compounds.
https://link.springer.com/article/10.1007%2Fs40820-019-0252-6
Mar 11, 2019 · With good biocompatibility, a silica-based drug delivery system was prepared and used effectively in vivo to prolong the duration of drug treatment. The prepared system can target spinal cord injury directly. Additionally, due to its small size (approximately 100 nm), it …Author: Guodong Sun, Shenghui Zeng, Xu Liu, Haishan Shi, Renwen Zhang, Baocheng Wang, Changren Zhou, Tao Yu
http://web.ics.purdue.edu/~jfleary/nanomedicine_course_2011/Lecture_5%20Core%20materials/Lecture%205%20References/Slowing_Mesoporous_NP_drug%20delivery-sensing.pdf
opment of controlled release and drug delivery devices using mesoporous silica nanomaterials, the effects of these materials on cellular development and propagation, and the difference in develop- ment between normal and cancer cells with the ultimate goal of controlling the release of antitumor drugs …
https://www.researchgate.net/publication/237080478_Silica_Particles_A_Novel_Drug-Delivery_System
Among the many stable biocompatible excipients, silica is generally the material of choice and has been studied in many drug delivery systems [9, 10]. Properties such as biocompatibility ...
https://www.sciencedirect.com/science/article/pii/S2211383517304926
Besides conventional drug delivery, mesoporous silica can also be applied as carrier for gene transfection. It is well known that carriers play an important role in gene delivery, since the naked nucleic acids show little penetration of cell membranes 100. There are two main gene delivery systems, namely viral and non-viral systems.Author: Yixian Zhou, Guilan Quan, Qiaoli Wu, Xiaoxu Zhang, Boyi Niu, Biyuan Wu, Ying Huang, Xin Pan, Chuanbi...
http://www.delsitech.com/technology/
Silica – The natural solution for drug delivery DelSiTech has developed a unique proprietary drug delivery technology based on biodegradable Silica (SiO …
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