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https://www.sciencedirect.com/topics/medicine-and-dentistry/acidosis
Acidosis is an important marker of severity in falciparum malaria infections. “Acidotic breathing” alone was associated with a 19% mortality rate in Kenyan children 17 (Fig. 101.4).Acidosis and hypoglycemia are strongly associated, suggesting parasite and/or host metabolism may be contributing to both.
https://malariajournal.biomedcentral.com/articles/10.1186/s12936-019-2733-y
Mar 25, 2019 · Lactic acidosis with an elevated lactate–pyruvate ratio suggesting anoxia is a common feature of severe falciparum malaria. High lactate levels are associated with parasitized erythrocyte sequestration in the microcirculation. To assess if there is an additional contribution to hyperlactataemia from relatively inadequate total oxygen delivery, oxygen consumption and delivery were ...Author: Hugh W. Kingston, Hugh W. Kingston, Hugh W. Kingston, Aniruddha Ghose, Voravut Rungpradubvong, Vorav...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391479/
Apr 09, 2015 · Introduction. Shock was recently redefined as a clinical state of acute circulatory failure with inadequate oxygen utilization and/or delivery by the cells resulting in cellular dysoxia/hypoxia [].In this setting, shock-associated lactic acidosis is the principal but not exclusive cause of metabolic acidosis in the shock state.Author: Antoine Kimmoun, Antoine Kimmoun, Emmanuel Novy, Thomas Auchet, Nicolas Ducrocq, Bruno Levy, Bruno L...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039774/
Safe delivery of two parturient women in severe metabolic acidosis ... We report two parturient women with severe metabolic acidosis which was considerably reduced very soon after the delivery and how our timely delivery resulted in the birth of two neurologically intact babies. ... We are advocating timely delivery in metabolic acidosis ...Author: Ina Ismiarti Shariffuddin, Vineya Rai, Y K Chan, Rajesh Kumar Muniandy
https://www.webmd.com/a-to-z-guides/what-is-metabolic-acidosis
When any of these happen, chemical reactions and processes in your body don't work right. Although severe episodes can be life-threatening, sometimes metabolic acidosis is a mild condition.
https://journals.lww.com/greenjournal/pages/articleviewer.aspx?year=2011&issue=10000&article=00008&type=Fulltext
We found that severe acidosis was associated with prior cesarean delivery, maternal age 35 years or older, prior neonatal death, thick meconium, uterine rupture, and abnormal fetal heart rate during labor. The frequency of severe acidosis (0.63%) was comparable to that found in other studies. 7, 14
https://www.medicalnewstoday.com/articles/320863
The onset of lactic acidosis might be rapid and occur within minutes or hours, or gradual, happening over a period of days. The best way to treat lactic acidosis is to find out what has caused it.
https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/acid-base-balance/acidosis
Severe acidosis may also be treated directly when it does not respond to efforts to treat the cause. In such cases, bicarbonate may be given intravenously. However, bicarbonate provides only temporary relief and may cause harm—for instance, by overloading the body with sodium and water. ... Insulin Delivery Diabetes is a condition that ...
https://fn.bmj.com/content/80/3/F246
May 01, 1999 · Disruption of any of these can cause fetal hypoxia, which, despite compensatory mechanisms, may lead to acidosis. When severe and acute (lasting hours), but especially if prolonged (days or weeks), hypoxia and therefore acidosis, are associated with significant morbidity and mortality with potential long term sequelae. ... Delivery before ...Author: Catherine S Bobrow, Peter W Soothill
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