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https://www.ncbi.nlm.nih.gov/pubmed/25426441
Development of self-microemulsifying drug delivery system and solid-self-microemulsifying drug delivery system of telmisartan. Jaiswal P(1), Aggarwal G(1), Harikumar SL(1), Singh K(1). Author information: (1)Deparment of Pharmaceutics, Rayat and Bahra Institute of …Author: Parul Jaiswal, Geeta Aggarwal, Sasidharan Leelakumari Harikumar, Kashmir Singh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241625/
Self-microemulsifying drug delivery system was diluted with distilled water in the ratio of 1:250, placed in a water bath and its temperature was increased gradually. Cloud point was measured as the temperature at which there was a sudden appearance of cloudiness visually. Robustness to dilution for self-microemulsifying drug delivery system
https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0208339
Specifically, Zhang et al. demonstrated the beneficial effects of the phospholipid complex on increasing the oil solubility of morin, a poorly water-soluble drug, enabling further development of a lipid-based emulsifying drug delivery system with high drug-payload. Self-microemulsifying drug delivery system (SMEDDS) has been considered as an ...Author: Ho Yong Son, Bo Ram Chae, Ji Yeh Choi, Dong Jun Shin, Yoon Tae Goo, Eun Seok Lee, Tae Hoon Kang, Cha...
https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0208339&type=printable
Optimization of self-microemulsifying drug delivery system for phospholipid complex of telmisartan using D-optimal mixture design Ho Yong Son 1☯, Bo Ram Chae , Ji Yeh Choi2, Dong Jun Shin1, Yoon Tae Goo1, Eun Seok Lee1, Tae Hoon Kang1, Chang Hyun Kim1, Ho Yub Yoon1, Young Wook Choi ID 1*Author: Ho Yong Son, Bo Ram Chae, Ji Yeh Choi, Dong Jun Shin, Yoon Tae Goo, Eun Seok Lee, Tae Hoon Kang, Cha...
https://www.hindawi.com/journals/jphar/2013/728425/
Sep 24, 2012 · Olmesartan medoxomil (OLM) is an angiotensin II receptor blocker (ARB) antihypertensive agent administered orally that has absolute bioavailability of only 26% due to the poor aqueous solubility (7.75 μ g/ml). The aim of the present investigation was to develop a self-microemulsifying drug delivery system (SMEDDS) to enhance the oral absorption of OLM.Author: Shailesh T. Prajapati, Harsh A. Joshi, Chhaganbhai N. Patel
https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.12115
Jul 24, 2013 · Objectives. To develop and optimize the novel self‐microemulsifying drug delivery system (SMEDDS) formulation for enhanced water solubility and bioavailability of telmisartan (TMS) using the Box–Behnken design (BBD) and desirability function.Author: Hyuk Jun Cho, Dong Won Lee, Nirmal Marasini, Bijay Kumar Poudel, Jeong Hwan Kim, Thiruganesh Ramasam...
http://ijpsr.com/bft-article/development-and-evaluation-of-self-nano-emulsifying-drug-delivery-system-for-telmisartan/?view=fulltext
DEVELOPMENT AND EVALUATION OF SELF NANO EMULSIFYING DRUG DELIVERY SYSTEM FOR TELMISARTAN HTML Full Text. DEVELOPMENT AND EVALUATION OF SELF NANO EMULSIFYING DRUG DELIVERY SYSTEM FOR TELMISARTAN . Girish Chandra Soni *1 and S. K. Prajapati 2. Sri Vankateshwara University 1, Meerut - 244236, Uttar Pradesh, India.
http://www.jsirjournal.com/Vol4_Issue3_09.pdf
Development and Characterization of Telmisartan Self-microemulsifying drug delivery system for Bioavailability Enhancement NiraliPadia, Arunkumar Shukla, PragnaShelat Abstract Telmisartan is a potent, long-lasting, nonpeptide antagonist of the angiotensin II type-1 (AT1) receptor that is indicated for the treatment of essential hypertension.
https://www.hindawi.com/journals/isrn/2014/964051/
Ease of administration and painless approach made oral route the most preferred. Poor oral bioavailability is pronounced with the majority of recent active ingredients because of dissolution rate limited absorption. Failure to attain intended therapeutic effect of the poor water soluble drugs by this route led to development of novel drug delivery systems which will fulfill therapeutic needs ...Author: Samatha Akula, Aravind Kumar Gurram, Srinivas Reddy Devireddy
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