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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/self-microemulsifying-drug-delivery-system
Self-microemulsifying drug delivery systems (SMEDDS) are designed to form an o/w microemulsion on dilution with an aqueous phase or GIT fluids upon oral administration, forming droplets in the nanosize range with high surface to volume ratio. The presence of …
http://www.pharmtech.com/self-emulsifying-drug-delivery-systems
Jul 02, 2008 · Among many such delivery options, like incorporation of drugs in oils (2), surfactant dispersion (3), emulsions (4) and liposomes (5), one of the most popular approaches are the self-emulsifying drug delivery systems (SEDDSs).
https://www.longdom.org/open-access/selfemulsifying-drug-delivery-systems-sedds-in-pharmaceuticaldevelopment-2090-4568-1000130.pdf
Self-Emulsifying Drug Delivery Systems (SEDDS) SEDDS are defined as a pre-concentrate containing a mixture of drug, oil, surfactant, co-surfactant and, sometimes, co-solventAuthor: Beatriz Zanchetta, Marco Vinícius Chaud, Maria Helena Andrade Santana
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1191.pdf
Drug molecules are either dissolved or suspended in the SELF system, which maintains the drug in very fine dispersion droplets inside the intestinal lumen, providing optimal conditions for absorption. SELF‐system exists: self emulsifying drug delivery systems (SEDDSs)‐micro‐emulsifying drug delivery systems (SMEDDSs).
https://www.ncbi.nlm.nih.gov/pubmed/31426272
Aug 16, 2019 · A Novel Self-Emulsifying Drug Delivery System (SEDDS) Based on VESIsorb® Formulation Technology Improving the Oral Bioavailability of Cannabidiol in Healthy Subjects. Knaub K(1), Sartorius T(2), Dharsono T(1), Wacker R(1), Wilhelm M(3), Schön C(1).Author: Katharina Knaub, Tina Sartorius, Tanita Dharsono, Roland Wacker, Manfred Wilhelm, Christiane Schön
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708959/
So, the aim of this study was to enhance the dissolution rate and oral hypoglycemic and hypolipidemic effect of resveratrol. This was achieved using self-emulsifying drug delivery system. The solubility of resveratrol was determined in various oils, surfactants, and cosurfactants.Author: Gehan F Balata, Ebtessam A Essa, Hanan A Shamardl, Samira H Zaidan, Mohammed As Abourehab
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2014.896058
Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to formulate poor water soluble compounds for bioavailability enhancement. However, certain limitations are associated with SMEDDS formulations which include in vivo drug precipitation,
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