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https://www.sciencedirect.com/science/article/pii/S0753332204000319
Self-Emulsifying Drug Delivery Systems 2.1. Excipients used in SEDDS. Self-emulsification has been shown to be specific to: the nature... 2.2. Mechanism of self-emulsification. The mechanism by which self-emulsification occurs is not... 2.3. Characterization of SEDDS. The primary means of ...Author: R Neslihan Gursoy, Simon Benita
https://www.longdom.org/open-access/selfemulsifying-drug-delivery-systems-sedds-in-pharmaceuticaldevelopment-2090-4568-1000130.pdf
drug bioavailability. Self-Emulsifying Drug Delivery Systems (SEDDS) SEDDS are defined as a pre-concentrate containing a mixture of drug, oil, surfactant, co-surfactant and, sometimes, co-solvent [18,26-30]. SEDDS is a broad term associated with the production of emulsions with a droplet size ranging from a few nanometers toFile Size: 540KB
https://www.ncbi.nlm.nih.gov/pubmed/15082340
The oral delivery of hydrophobic drugs presents a major challenge because of the low aqueous solubility of such compounds. Self-emulsifying drug delivery systems (SEDDS), which are isotropic mixtures of oils, surfactants,...Author: R Neslihan Gursoy, Simon Benita
https://www.sciencedirect.com/science/article/abs/pii/S0753332204000319
Dossier: Drug delivery and drug efficacy. Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Abstract. The oral delivery of hydrophobic drugs presents a major challenge because of the low aqueous solubility of such compounds.Author: R Neslihan Gursoy, Simon Benita
https://www.ncbi.nlm.nih.gov/pubmed/31426272
Aug 16, 2019 · To overcome these limitations a novel self-emulsifying drug delivery system (SEDDS) based on VESIsorb® formulation technology incorporating CBD, as Hemp-Extract, was developed (SEDDS-CBD). The study objective was to evaluate the pharmacokinetic profile of SEDDS-CBD in a randomized, double-blind, cross-over design in 16 healthy volunteers under fasted conditions.Author: Katharina Knaub, Tina Sartorius, Tanita Dharsono, Roland Wacker, Manfred Wilhelm, Christiane Schön
http://sphinxsai.com/2014/PTVOL6/PT=20(546-568)AJ14.pdf
SELF EMULSIFYING DRUG DELIVERY SYSTEMS (SEDDS) SEDDS belong to lipid-based formulations. Lipid formulations can be oils, surfactant dispersions, emulsions, solid lipid nanoparticles and liposomes. SEDDS are isotropic mixtures of drug, lipids and surfactants, usually with one or more hydrophilic co-solvents or co-emulsifiers.File Size: 593KB
https://www.researchgate.net/publication/41411253_Self-Emulsifying_Drug_Delivery_Systems_SEDDS_Formulation_Development_Characterization_and_Applications
Self-Emulsifying Drug Delivery Systems (SEDDS): Formulation Development, Characterization, and Applications 1. Thermodynamic Stability Studies. 2. Robustness to Dilution.
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