Self-Emulsifying Drug Delivery System For Paclitaxel

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Enhanced oral absorption of paclitaxel in a novel self ...

    https://www.ncbi.nlm.nih.gov/pubmed/15032307
    Enhanced oral absorption of paclitaxel in a novel self-microemulsifying drug delivery system with or without concomitant use of P-glycoprotein inhibitors. Yang S(1), Gursoy RN, Lambert G, Benita S. Author information: (1)Department of Pharmaceutics, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.Author: Shicheng Yang, R. Neslihan Gursoy, Gregory Lambert, Simon Benita

Preparation and Evaluation of Solid-Self-Emulsifying Drug ...

    https://www.hindawi.com/journals/jnm/2016/3642418/
    Solid-self-emulsifying drug delivery system (S-SEDDS) of paclitaxel (Ptx) was developed by the spray drying method with the purpose of improving the low bioavailability (BA) of Ptx. 10% oil (ethyl oleate), 80% surfactant mixture (Tween 80 : Carbitol, 90 : 10, w/w), and 10% cosolvent (PEG 400) were chosen according to their solubilizing capacity.Author: Hea-Young Cho, Jun-Hyuk Kang, Lien Ngo, Phuong Tran, Yong-Bok Lee

Self-emulsifying drug delivery systems (SEDDS) for ...

    https://www.sciencedirect.com/science/article/pii/S0753332204000319
    In fact, the most popular approach is the incorporation of the drug compound into inert lipid vehicles such as oils , surfactant dispersions , , self-emulsifying formulations , , , ], emulsions , , , , and liposomes with particular emphasis on self-emulsifying drug delivery systems (SEDDS).Author: R Neslihan Gursoy, Simon Benita

Formulation optimization of Docetaxel loaded self ...

    https://www.nature.com/articles/srep26895
    May 31, 2016 · Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity Skip to main content Thank you for visiting nature.com.Author: Guru R. Valicherla, Guru R. Valicherla, Kandarp M. Dave, Anees A. Syed, Mohammed Riyazuddin, Anand P...

Self Emulsifying Drug Delivery System: A Recent Approach

    https://www.researchgate.net/publication/331384576_Self_Emulsifying_Drug_Delivery_System_A_Recent_Approach
    Self Emulsifying Drug Delivery System: A Recent Approach. ... The SE nanoparticles of paclitaxel by emulsion solv ent. evaporation using chitosan and glycer yl monooleate were obser-

Paclitaxel Nano-Delivery Systems: A Comprehensive Review

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806207/
    Feb 18, 2013 · Paclitaxel and its Limitations. Paclitaxel (PX), isolated from the bark of Pacific Yew (Taxus brevifolia), which was first discovered by Mrs. Monroe E. Wall and Mansukh C. Wani, is a white crystalline powder with the melting point of ~210°C (Figure 1).It is one of the most effective chemotherapeutic drugs and is mainly used to treat lung, ovarian, and breast cancer, etc [].Author: Ping Ma, Russell J. Mumper

Excipient effects on in vitro cytotoxicity of a novel ...

    https://www.sciencedirect.com/science/article/pii/S0022354916313661
    The objective of this work was to develop a novel self‐emulsifying drug delivery system (SEDDS) devoid of cremophor for the i.v./oral delivery of paclitaxel and to investigate the in vitro cytotoxicity of the combined excipients. The SEDDS formulations were characterized in terms …Author: Neslihan Gursoy, Jean‐Sebastien Garrigue, Alain Razafindratsita, Gregory Lambert, Simon Benita

(PDF) Self emulsifying drug delivery system: A review

    https://www.researchgate.net/publication/284968090_Self_emulsifying_drug_delivery_system_A_review
    Self emulsifying drug delivery system: A review ... paclitaxel. These nanoparticles p ossessed bioadhesive properties & incr eased cellular . association of the drug 29-solvent evaporation method. 1.

SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW ...

    http://ijpsr.com/bft-article/self-emulsifying-drug-delivery-system-a-review/?view=fulltext
    SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW HTML Full Text. SELF EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW. Kshitija Khedekar* 1 andSwati Mittal 2 Department of Quality Assurance 1, Department of Pharmaceutics 2, Vivekanand Education Society’s College of Pharmacy, Chembur, Mumbai, Maharashtra, India

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