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http://www.pharmtech.com/self-emulsifying-drug-delivery-systems
Jul 02, 2008 · Self-emulsifying drug delivery systems (SEDDSs) have gained exposure for their ability to increase solubility and bioavailability of poorly soluble drugs. SEDDSs are isotropic mixtures of oils and surfactants, sometimes containing cosolvents, and can …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674636/
Feb 06, 2015 · SEDDS is a stable mixture of drug, oil, surfactant, and co-surfactant; while self-microemulsifying drug delivery system (SMEDDS) is SEDDS which can form fine oil-in-water droplets with a diameter size of less than 50 nm under mild agitation of the gastrointestinal tract without the dissolution process ( 13 ).Author: Lan Wu, Yanli Qiao, Lina Wang, Jiahua Guo, Guocheng Wang, Wei He, Lifang Yin, Jinhua Zhao
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/self-microemulsifying-drug-delivery-system
Self-microemulsifying drug delivery systems (SMEDDS) are designed to form an o/w microemulsion on dilution with an aqueous phase or GIT fluids upon oral administration, forming droplets in the nanosize range with high surface to volume ratio. The presence of …
https://www.longdom.org/open-access/selfemulsifying-drug-delivery-systems-sedds-in-pharmaceuticaldevelopment-2090-4568-1000130.pdf
Lipid-based formulations, such as Self-Emulsifying Drug Delivery Systems (SEDDS), are an important tool for lipophilic drugs and offer the potential for enhancing drug absorption and oral bioavailability.File Size: 540KB
https://innovareacademics.in/journal/ijpps/Vol3Suppl2/1191.pdf
Drug molecules are either dissolved or suspended in the SELF system, which maintains the drug in very fine dispersion droplets inside the intestinal lumen, providing optimal conditions for absorption. SELF‐system exists: self emulsifying drug delivery systems (SEDDSs)‐micro‐emulsifying drug delivery systems (SMEDDSs).
https://www.sciencedirect.com/science/article/pii/S0169409X96004905
Self-emulsifying drug delivery systems (SEDDS) are mixtures of oils and surfactants, ideally isotropic, sometimes including cosolvents, which emulsify under conditions of gentle agitation, similar to those which would be encountered in the gastro-intestinal tract.Author: Colin W. Pouton
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