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https://www.aliem.com/2018-acep-policy-non-st-elevation-acs/#:~:text=Repeat%20troponin%20testing%20within%203%20hours%20of%20ED,single%20UNDETECTABLE%20value%20at%20time%200%20is%20enough.
https://heart.bmj.com/content/102/16/1253
High-sensitivity cardiac troponin at 3 hours: is the cat among the pigeons? In November 2014, the National Institute for Health and Care Excellence (NICE) issued recommendations for the use of high-sensitivity cardiac troponin (hs-cTn) assays in the UK. 1 Two assays were evaluated: the Elecsys hs-cTnT assay (Roche Diagnostics) and the …
https://www.stemlynsblog.org/nice-high-sensitivity-troponin/
Troponin can’t help you to diagnose unstable angina because patients with that diagnosis have, by definition, no rise and/or fall of troponin. This means that you still need to do some thinking. Not everyone who has normal troponin levels at 3 hours can go home. If the patients are high risk, you should still be admitting them to hospital.
https://pubmed.ncbi.nlm.nih.gov/23063209/
For rule-in a 3-hour protocol performed as well as a 6-hour protocol, with a significantly (p<0.0001) better performance of absolute (AUC 0.851 vs. 0.845, p=0.740) as compared to relative concentration changes (AUC 0.771 vs. 0.739, p=0.169). Conclusions: Rule-in and rule-out of non-STEMI may be accomplished comparably effective at 3 or 6h. For rule-in, absolute …
https://www.medscape.com/answers/155919-15143/how-often-should-cardiac-troponins-be-measured-after-the-initial-level-is-obtained-at-presentation
Serial measurement of cardiac troponins after the initial level is obtained at presentation, 3 to 6 hours after symptom onset, is recommended. If initial levels are …
https://litfl.com/troponin-in-critical-illness/
Lower sensitivity troponin requires at least 6 hours between time of initial lab and repeat troponin to see a conclusive increase to rule in AMI Serial sampling of high sensitivity tropinin at 0 and 2 hours can safely rule-out of AMI (can be discharged if TIMI 0 or 1, and normal ECG) References and Links LITFL LITFL CCC — Cardiac biomarkers
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