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https://www.researchgate.net/publication/317369587_ROLE_OF_MATHEMATICAL_MODELLING_IN_CONTROLLED_RELEASE_DRUG_DELIVERY
ROLE OF MATHEMATICAL MODELLING IN CONTROLLED RELEASE DRUG DELIVERY ... Mathematical modelling of controlled drug delivery can help prov ide a ... “Modeling of drug release from delivery systems ...
https://www.researchgate.net/publication/242784947_Role_of_Mathematical_Modeling_in_Controlled_Drug_Delivery
Mathematical modeling of controlled drug delivery can help to provide a scientific knowledge base concerning the mass transport mechanisms that are involved in the control of drug release.
https://www.ncbi.nlm.nih.gov/pubmed/16305412
1. Curr Drug Deliv. 2005 Jan;2(1):97-116. Mathematical modelling and controlled drug delivery: matrix systems. Grassi M(1), Grassi G. Author information: (1)Department of Chemical Engineering (DICAMP) University of Trieste, Piazzale Europa 1, Trieste, I-34127, Italy. [email protected] This paper deals with the physical and mathematical modelling description of drug release from ...Author: Mario Grassi, Gabriele Grassi
http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.605.5690
CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Controlled drug delivery occurs when a polymer or lipid (natural or synthetic) is judiciously combined with a drug or other active agent in such a way that the active agent is released from the material in a pre-designed manner. The aim of controlling the drug delivery is to achieve more effective therapies while ...
https://www.sciencedirect.com/science/article/pii/S0168365911009588
1. Introduction. The mechanistic realistic mathematical description of mass transport in controlled drug delivery systems can be highly beneficial , , , , : firstly, it can allow getting deeper insight into the mechanisms, which control drug release from a particular type of dosage forms , , , , , , , , .Thus, the safety of the respective treatment can be improved.Author: Juergen Siepmann, Juergen Siepmann, Florence Siepmann, Florence Siepmann
https://www.sciencedirect.com/science/article/pii/S0378517308006169
The mathematical modeling of drug delivery has a significant potential to facilitate product development in the future and to help understanding complex pharmaceutical dosage forms. Due to the advances in information technology the accuracy of these models steadily increases and …Author: J. Siepmann, F. Siepmann
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518665/
Jan 10, 2013 · This review aims to highlight mechanistic, mathematical models that address the role of autocatalysis in the mass transport and chemical reaction phenomena of drug delivery from PLGA microspheres. The place of these types of models in the broader context of mathematical models for polymeric drug delivery systems is illustrated in Fig. 3.Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
https://web.mit.edu/braatzgroup/mathematical_modeling_of_drug_delivery_from_autocatalytically_degradable_plga_microspheres_a_review.pdf
PLGA microspheres are widely studied for controlled release drug delivery applications, and many models have been proposed to describe PLGA degradation and erosion and drug release from the bulk polymer. Au-tocatalysis is known to have a complex role in the dynamics of PLGA erosion and drug transport and can lead
https://www.mdpi.com/journal/gels/special_issues/model_hydrogels
Dear Colleagues, Mathematical modeling has played a key role in the engineering and design of hydrogels for controlled drug delivery. Mathematical models enable understanding of the critical physical phenomena involved in drug delivery systems and, once their predictive capability has been established, they can be used for the rational design of the device according to the desired performances.
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1567-2018&volume=2&issue=1&spage=97
Abstract: This paper deals with the physical and mathematical modelling description of drug release from matrix systems. In the introduction, matrix systems are considered in the wide frame of the controlled release systems and the concept of mathematical model is briefly discussed.
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