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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2977003/
Jun 11, 2010 · The site of action of siRNA therapeutics is the cytosol. The barriers to siRNA delivery are multiple and depend on the targeted organs and the administration routes. In general, locoregional delivery of siRNA has fewer barriers compared to systemic delivery.Author: Jie Wang, Ze Lu, M. Guillaume Wientjes, Jessie L.-S. Au
https://www.businesswire.com/news/home/20100202005471/en/Dicerna-Present-New-Data-Dicer-Substrate-siRNA
Dicerna to Present New Data on Dicer Substrate siRNA Molecules at Cambridge Healthtech Institute’s Second Annual RNA Interference: From Tools to Therapies Conference ... RNAi Delivery” on ...
https://rnaitherapeutics.blogspot.com/2010/
Nov 30, 2010 · To quote from Alnylam’s press release yesterday, on research presented at the 8 th International M. Judah Folkman Conference ‘The new research demonstrated effective silencing of target genes in distinct cell types and tissues beyond the liver with …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717312/
The eighth annual RNAi international conference and exhibition, RNAi2013 was hosted at St Hilda's College, Oxford, UK (19-21 March 2013), and provided a platform for congregation of researchers with both academic and industrial backgrounds to share and discuss their most recent work in the fast advancing field of RNAi.Author: Laura A Mulcahy, David Rf Carter
https://www.businesswire.com/news/home/20101008005385/en/Alnylam-Scientists-Present-New-Research-Expanded-Delivery
“One of our key achievements over the past 12 months is the major progress we and our collaborators have made in advancing systemic delivery of RNAi therapeutics.
https://rnaitherapeutics.blogspot.com/2010/05/
May 25, 2010 · The resuscitation of KL means that Alnylam may leverage this patent as potentially gate-keeping as it looks to enter additional non-exclusive licensing partners for its dominant RNAi Therapeutics patent portfolio, also as a potential backstop in the unlikely event that Alnylam loses the fight for the key Tuschl inventions.
https://iopscience.iop.org/journal/0957-4484/page/Focus-RNAi
Delivery of EG5 siRNA into Huh7 cells resulted in antitumoral activity with G2/M arrest, triggered by loss of mitotic spindle separation and formation of mono-astral spindles. These findings demonstrate the potential of GE11 ligand-containing RNAi polyplexes for cancer treatment.
https://www.aquaculturealliance.org/advocate/studies-seek-oral-delivery-of-rnai-based-therapeutics-for-shrimp/
Oral delivery of RNAi therapeutics. Unfortunately, the delivery of potential RNAi-based therapeutics via injection is impractical. Oral delivery approaches are likely to be a more viable option in shrimp aquaculture. To date, simple methods for the oral delivery of dsRNA to Pacific white shrimp have not proven successful and reproducible.
https://mirnablog.com/rnai-mirna-and-sirna-conference-london/
RNAi, miRNA and siRNA 27 Jun 2011 – 28 Jun 2011 – London, UK Copthorne Tara Hotel. The conference will address: RNA-based therapeutics; siRNA and oligoneucleotide delivery
https://www.sciencedirect.com/science/article/pii/S0168365914005677
Current issues of RNAi therapeutics delivery and development. Author links open overlay ... presentation provides an update on the current state of RNAi therapeutics development with a particular focus on what RNAi delivery can achieve today and key challenges to be overcome to expand therapeutic opportunities. ... 107 (2010), p. 1864. Google ...Author: D. Haussecker
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