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https://en.wikipedia.org/wiki/Rimonabant
Rimonabant (also known as SR141716; trade names Acomplia, Zimulti) is an anorectic antiobesity drug that was first approved in Europe in 2006 but was withdrawn worldwide in 2008 due to serious psychiatric side effects; it was never approved in the United States. Rimonabant is an inverse agonist for the cannabinoid receptor CB1 and was the first drug approved in that class.Formula: C₂₂H₂₁Cl₃N₄O
https://pubchem.ncbi.nlm.nih.gov/compound/Rimonabant
Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid receptor CB1. Its main avenue of effect is reduction in appetite. Rimonabant is the first selective CB1 receptor blocker to be approved for use anywhere in the world.
https://www.drugs.com/acomplia.html
Sanofi-Aventis has withdrawn rimonabant from the market globally and it is no longer under development. 1 Acomplia was officially withdrawn by the European Medicines Agency (EMEA) in January 2009 due to the risks of dangerous psychological side effects, including suicidality. Previously, the EMEA had suspended Acomplia from the UK market in 2008 because the agency felt the benefits did not ...
https://www.sciencedirect.com/topics/neuroscience/rimonabant
Rimonabant has been reported to cause partial seizures in a patient with a history of generalized epilepsy [115 A]. A 52-year-old obese man with hypertension, diabetes mellitus, and a history of absences and two generalized tonic–clonic seizures at ages 4–15 years, but who had been seizure free for over 20 years took rimonabant 20 mg/day and 2 months later started to have nocturnal partial ...
http://www.getraws.com/rimonabant-powder-p-70.html
Safest and Fastest Delivery. Parcels can be sent out within 24 hours after the payment, tracking number and packing picture would be informed soon afterwards. ... Descriptions about SR141716 Acomplia Rimonabant Rimonabant is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. It is an inverse agonist for the cannabinoid ...
https://www.ncbi.nlm.nih.gov/pubmed/19578688
1. Rev Bras Psiquiatr. 2009 Jun;31(2):145-53. The psychiatric side-effects of rimonabant. Moreira FA(1), Crippa JA. Author information: (1)Department of Pharmacology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil. OBJECTIVE: Experimental evidence has suggested that drugs that enhance cannabinoid type-1 (CB1) receptor activity may induce ...Author: Fabrício A. Moreira, José Alexandre S. Crippa
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012438/
Feb 29, 2008 · Evidence from animal models suggests that overactivity of the endocannabinoid system may be associated with obesity, and that blockade of endocannabinoid CB1 receptors is associated with reductions in food intake and body weight (Kirkham & Williams 2004). Rimonabant (SR-141716A; Acomplia ®, Sanofi-Aventis) is a novel CB1 antagonist. This ...Author: Mark Waterlow, Paul Chrisp
https://www.consumerhealthdigest.com/weight-loss-reviews/rimonabant.html
Rimonabant is formulated from the following ingredients which are known to support rapid weight loss in the body safely: Rimonabant – This is the active ingredient in the supplement and also where it gets its name from. It helps in suppressing the user’s appetite and also increasing metabolism in the body leading to increased rate of ...
https://www.drugs.com/history/zimulti.html
Zimulti (rimonabant) is a cannabinoid-1 receptor blocker (CB1) intended for use in the treatment of obesity, smoking cessation, and related conditions. Sanofi-Aventis has withdrawn rimonabant from the market globally and it is no longer in development. In June 2007, the FDA's Endocrine and Metabolic Drugs Advisory Committee recommended against ...
https://www.medchemexpress.com/Rimonabant.html
Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). - Mechanism of Action & Protocol.
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