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https://www.sciencedirect.com/science/article/pii/S0079670008000609
Drug-delivery systems responsive to temperature utilize various polymer properties, including the thermally reversible transition of polymer molecules, swelling change of networks, glass transition and crystalline melting .Author: A.K. Bajpai, Sandeep K. Shukla, Smitha Bhanu, Sanjana Kankane
https://www.researchgate.net/publication/222546361_Responsive_Polymers_in_Controlled_Drug_Delivery
This article reviews the state-of-the art in responsive polymer systems for controlled drug delivery applications. The paper describes different types of stimuli-sensitive systems and gives an account of their synthesis through methods such as group transfer polymerization,...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6681499/
Jul 12, 2019 · Poly(N-isopoprylacrilamide) (pNIPAAm), which is a synthetic thermo-responsive polymer can form hydrogel at or near the body temperature . pNIPAAm is the mostly studied and FDA-approved, widely applied thermo-responsive polymer for drug delivery applications [24,104,105].Author: Sudipta Chatterjee, Patrick Chi-leung Hui
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
The majority of responsive polymers for drug delivery can be broadly categorized as hydrogels, micelles, polyplexes, or polymer-drug conjugates, which are covered in more detail below. Hydrogels are hydrophilic (co)polymeric networks capable of imbibing large amounts of water or biological fluids …Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.sciencedirect.com/science/article/pii/S0169409X06001839
Stimuli-responsive polymers offer great advantages in drug delivery. Instead of acting passively as pure drug carriers, they will interact and respond to the environmental setting. This allows us to aim further for tailor-made drug delivery with superior pharmacokinetics while …Author: Dirk Schmaljohann
https://www.sciencedirect.com/science/article/pii/S2211383514000252
Review Smart polymers for the controlled delivery of drugs – a concise overview 1. Introduction. Pharmaceutical and biological therapeutics are often limited by short half-lives,... 2. Stimuli-responsive polymers. A stimuli-sensitive or smart polymer undergoes an abrupt change in... 3. ...Author: Honey Priya James, Rijo John, Anju Alex, K.R. Anoop
https://www.mddionline.com/polymers-controlled-drug-delivery
Originally, polylactides and polyglycolides were used as absorbable suture material, and it was a natural step to work with these polymers in controlled drug delivery systems. The greatest advantage of these degradable polymers is that they are broken down into biologically acceptable molecules that are metabolized and removed from the body via normal metabolic pathways.
https://japsonline.com/admin/php/uploads/495_pdf.pdf
Controlled drug delivery is useful because it allows to obtain better drug product effectiveness, reliability and safety. Interest in stimuli-responsive polymers is steadily gaining
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912992/
Anionic polymers responsive to intestinal high pH are used for preventing gastric degradation of drug, colon drug delivery and achieving high bioavailability of weak basic drugs. Tumor-targeted DDSs have been developed based on polymers with imidazole groups or poly (β-amino ester…Author: Takayuki Yoshida, Tsz Chung Lai, Glen S Kwon, Kazuhiro Sako
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425417/
Nov 07, 2014 · Well recognized advantages of nanoscale particles include sustained drug delivery, 7 hydrophilic and hydrophobic multi-drug co-incorporation and programmed-delivery, 8, 9 prolonged circulation time in vivo, the ability to be engineered with functionalized ligands 10, 11 and stimuli-responsive controlled drug release. 12, 13 Among myriads of successful applications, stimuli …Author: Quanyin Hu, Prateek S. Katti, Zhen Gu
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