Responsive Drug Delivery

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Enzyme-Responsive Nanomaterials for Controlled Drug Delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425417/
    Nov 07, 2014 · For example, pH-responsive nanomaterials have been used to design sensitive nano-systems for drug delivery in cancer therapy as they can stabilize the drug at physiological pH and release the drug when the pH trigger point is reached. 14 Due to the lower pH values in the tumor microenviroment compared to normal tissue, pH-responsive ...Author: Quanyin Hu, Prateek S. Katti, Zhen Gu

Stimuli-responsive nanocarriers for drug delivery, tumor ...

    http://www.thno.org/v10p4557.htm
    Enzyme responsive drug delivery system based on mesoporous silica nanoparticles for tumor therapy in vivo. Nanotechnology. 2015;26:145102 294. Nguyen MM, Carlini AS, Chien MP, Sonnenberg S, Luo C, Braden RL. et al. Enzym-responsive nanoparticles for targeted accumulation and prolonged retention in heart tissue after myocardial infarction. Adv ...

Stimuli-responsive nanocarriers for drug delivery Nature ...

    https://www.nature.com/articles/nmat3776
    Oct 23, 2013 · Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become possible.Author: Simona Mura, Julien Nicolas, Patrick Couvreur

ATP-Responsive Drug Delivery Systems

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4998835/
    ATP responsive drug delivery systems To make a nanocarrier responsive to ATP, functional modules capable of differentiating ATP from other cytosolic components need to be incorporated. By far, two types of modules were adopted based on the specific recognition of ATP by biomacromolecules: 1) single stranded DNA (ssDNA) aptamers that ...Author: Wujin Sun, Zhen Gu

Electro-responsive drug delivery from hydrogels ...

    https://www.sciencedirect.com/science/article/pii/S0168365903003031
    Electro-responsive drug delivery has been demonstrated in vivo, in rats, where a subcutaneously implanted hydrogel released its drug load in a pulsatile fashion following the application of an external electric field . Fasted, anaesthetised rats were shaved on the back and the abdomen and ventral (anode) and dorsal (cathode) electrodes were ...Author: Sudaxshina Murdan

Stimuli-Responsive Nano-Architecture Drug-Delivery Systems ...

    https://pubs.acs.org/doi/abs/10.1021/acsnano.8b06104
    The microenvironment characteristics of solid tumors, renowned as barriers that harshly impeded many drug-delivery approaches, were precisely studied, investigated, categorized, divided, and subdivided into a complex diverse of barriers. These categories were further studied with a particular perspective, which makes all barriers found in solid-tumor micromilieu turn into different types of ...Author: Hossam S. El-Sawy, Ahmed M. Al-Abd, Tarek A. Ahmed, Tarek A. Ahmed, Khalid M. El-Say, Khalid M. El-S...

pH-Responsive carriers for oral drug delivery: challenges ...

    https://www.tandfonline.com/doi/full/10.1080/10717544.2017.1279238
    Dec 19, 2012 · In this review, we deal with the possibilities being explored in the pH-responsive oral drug delivery systems prepared from organic polymers or inorganic materials, the challenges in their development and future prospects, with focus on technology trends to improve the bioavailability of orally delivered drugs, the mechanisms of drug release ...Author: Lin Liu, WenDong Yao, YueFeng Rao, XiaoYang Lu, JianQing Gao

Construction of redox-responsive tumor targeted cisplatin ...

    https://www.sciencedirect.com/science/article/pii/S0378517320301745
    The nano-delivery system HA-(BPEI-SS-Pt)-1/4 for cisplatin has been developed for effective cancer chemotherapy. HA-(BPEI-SS-Pt)-1/4 showed specific tumor-targeting ability, redox-responsive drug release manner, and more effective antitumor performance along with minor side effects and systemic toxicity compared with cisplatin, which is of great significance for the chemotherapeutic drug in ...Author: Yi-Yang Jia, Jun-Jie Zhang, Ya-Xuan Zhang, Wei Wang, Chen Li, Si-Yuan Zhou, Bang-Le Zhang

Stimuli Responsive Polymeric Nanocarriers for Drug ...

    https://www.elsevier.com/books/stimuli-responsive-polymeric-nanocarriers-for-drug-delivery-applications/makhlouf/978-0-08-101995-5
    As innovation and development in the area of stimuli responsive polymer-based nanomaterials for drug delivery is moving fast and there is an increased global demand for biodegradable and biocompatible responsive polymers and nanoparticles for safe drug delivery, users will find this to be a timely resource.5/5

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