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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500532/
Progress in the development of remotely-triggered drug delivery systems has been enabled by cross-disciplinary studies in nanotechnology, materials science and chemistry, and these systems have been designed to react to a wide range of stimuli. For example, ...Author: Brian P. Timko, Brian P. Timko, Daniel S. Kohane
https://www.ncbi.nlm.nih.gov/pubmed/23149010
CONCLUSIONS: Advances in remotely-triggered drug delivery have been brought about by the convergence of numerous scientific and engineering disciplines, and this convergence is likely to play an important part in the current trend to develop systems that provide more than one therapeutic modality.Author: Brian P. Timko, Brian P. Timko, Daniel S. Kohane
https://www.nature.com/articles/natrevmats201720
May 09, 2017 · Drug delivery systems that are externally triggered to release drugs and/or target tissues hold considerable promise for improving the treatment of …Author: Yanfei Wang, Daniel S. Kohane
https://www.nichd.nih.gov/about/meetings/2019/042419
Remotely targeted and triggered drug delivery systems have become areas of considerable interest. This webinar will review the rationales for such systems and their characteristics, when used for local or systemic drug delivery.
https://sites.tufts.edu/timkolab/files/2018/09/Timko_ExpertOpinionDrugDelivery_2014.pdf
Remotely triggered drug delivery devices have recently been realized as injectable or implantable formulations that enable the patient or physician to control the timing and dose of drug release over an extended period. Such devices could increase patient compliance, maximize therapeutic effec-
https://www.pnas.org/content/114/47/12419
Nov 21, 2017 · Remotely controlled, localized drug delivery is highly desirable for potentially minimizing the systemic toxicity induced by the administration of typically hydrophobic chemotherapy drugs by conventional means. Nanoparticle-based drug delivery systems provide a highly promising approach for localized drug delivery, and are an emerging field of ...Author: Amanda M. Goodman, Oara Neumann, Kamilla Nørregaard, Luke Henderson, Mi Ran Choi, Susan E. Clare, Na...
https://www.sciencedirect.com/science/article/pii/S0928493118325517
In this study, polyelectrolyte multilayers were incorporated with HAP microcapsules to prepare remotely controllable drug delivery vehicles . The introduction of HAP and natural polyelectrolytes would assuage the initial burst drug release and improve the pH-responsive property of the hybrid microcapsules.Author: Xiaoyi Zhu, Jun Shi, He Ma, Ruixia Chen, Jingguo Li, Shaokui Cao
https://www.researchgate.net/publication/46149981_Remotely_Triggerable_Drug_Delivery_Systems
Remotely Triggerable Drug Delivery Systems. ... A remotely triggered drug release system with dot array-like configuration for controlled release of multiple drugs. Article.
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/adma.201002072
Triggerable drug delivery systems enable on‐demand controlled release profiles that may enhance therapeutic effectiveness and reduce systemic toxicity. Recently, a number of new materials have been developed that exhibit sensitivity to visible light, near‐infrared (NIR) light, ultrasound, or magnetic fields.Author: Brian P. Timko, Brian P. Timko, Tal Dvir, Tal Dvir, Daniel S. Kohane, Daniel S. Kohane
https://www.pnas.org/content/pnas/114/47/12419.full.pdf
for uptake of drug molecules in a host–guest manner (22–24). Host-conjugated nanoparticles can provide efficient internali-zation into cells and provoke less of an immune response than free drug molecules (25–29). For remotely triggered drug de-livery, equally important is the nanoparticle’s light-induced drug-release mechanism.Author: Amanda M. Goodman, Oara Neumann, Kamilla Nørregaard, Luke Henderson, Mi Ran Choi, Susan E. Clare, Na...
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