Rational Design Of Particulate Delivery System For Biopharmaceuticals

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Structure–function relationships to guide rational design ...

    https://www.sciencedirect.com/science/article/pii/S0924224409001782
    The rational design and fabrication of food-grade delivery systems can draw extensively from the knowledge gained through the development of drug delivery systems. This review provides a concise overview of particulate delivery systems and outlines current research trends linking their structural properties to their functionality, e.g. , matrix ...Author: Uri Lesmes, David Julian McClements

Functionalized materials for multistage platforms in the ...

    https://www.sciencedirect.com/science/article/pii/S0079642517300567
    Thus, to successfully fulfill the oral delivery of biopharmaceuticals, there is the need to evolve and take advantage of the enormous progress made in materials science, to design “smart” particulate drug delivery systems that can respond to the gastrointestinal environmental characteristics.Author: Francisca Araújo, José das Neves, Joao Pedro Oliveira Martins, Pedro L. Granja, Helder Almeida Santo...

Mingshi Yang - Manufacturing and Materials

    https://pharmacy.ku.dk/employees/manufacturing-and-materials/?pure=en/persons/322079
    Rational design of particulate delivery system for biopharmaceuticals (Feng Wan, 2011-2014) main supervisor; Design of functional lipid nanoparticles for oral delivery of protein/peptide drugs and study of absorption mechanism (Xiuying Li, 2010-2014) co-supervisor in collaboration with Shanghai Institute of Materia Medica, Chinese Academy of ...

Mingshi Yang - Ansatte

    https://farmaci.ku.dk/ansatte/?pure=da%2Fpersons%2Fmingshi-yang(07289bb0-ef6d-4f68-9637-619db9ed227c).html
    Rational design of particulate delivery system for biopharmaceuticals (Feng Wan, 2011-2014) main supervisor; Design of functional lipid nanoparticles for oral delivery of protein/peptide drugs and study of absorption mechanism (Xiuying Li, 2010-2014) co-supervisor in collaboration with Shanghai Institute of Materia Medica, Chinese Academy of ...

Drug Delivery Systems for Biopharmaceuticals BioPharm ...

    http://www.biopharminternational.com/drug-delivery-systems-biopharmaceuticals
    Aug 01, 2015 · Industry experts spoke to BioPharm International about the key considerations in the development of a drug-delivery device for a biologic drug, the importance of human factors engineering, the advantages of prefilled syringes, and the challenges in the manufacture of these devices.

(PDF) Intravascular Delivery of Particulate Systems: Does ...

    https://www.researchgate.net/publication/23179871_Intravascular_Delivery_of_Particulate_Systems_Does_Geometry_Really_Matter
    Intravascular Delivery of Particulate Systems: Does Geometry Really Matter? ... particle geometry in systemic delivery. Rational design of particulate systems should consider, beside the physico ...

Rational design and optimization of downstream processes ...

    https://www.researchgate.net/publication/51516469_Rational_design_and_optimization_of_downstream_processes_of_virus_particles_for_biopharmaceutical_applications_Current_advances
    We review the current options for downstream processing of these complex biopharmaceuticals and underline current advances on knowledge-based toolboxes proposed for rational optimization of their ...

Expert Review Intravascular Delivery of Particulate ...

    https://link.springer.com/content/pdf/10.1007%2Fs11095-008-9697-x.pdf
    in systemic delivery. Rational design of particulate systems should consider, beside the physico-chemical properties of the surface coatings, geometrical features as size and shape. The integration of mathematical modeling with in-vitro and in-vivo testing provides the tools for establishing a rational design of nanoparticles.Author: Paolo Decuzzi, Renata Pasqualini, Wadih Arap, Mauro Ferrari, Mauro Ferrari

Intravascular Delivery of Particulate Systems: Does ...

    https://www.deepdyve.com/lp/springer-journals/intravascular-delivery-of-particulate-systems-does-geometry-really-9KXokFwFFb
    Aug 20, 2008 · Read "Intravascular Delivery of Particulate Systems: Does Geometry Really Matter?, Pharmaceutical Research" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Rational Design of Biopharmaceutical Formulations ...

    https://bioprocessintl.com/manufacturing/formulation/rational-design-of-liquid-protein-biopharmaceutical-formulations-application-of-biophysical-stability-predictors-and-descriptors-to-reformulate-biotherapeutics/
    Rational Design of Liquid Protein Formulations: Application of Biophysical Stability Predictors and Descriptors to Reformulate Biotherapeutics ... those studies are based on key biophysical descriptors and extended particulate characterization methods ... Product differentiation also can come with design of an improved delivery system, a high ...

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