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https://www.drugs.com/propofol.html#:~:text=Propofol%20causes%20severe%20drowsiness%20and%20dizziness%2C%20which%20may,hours%20after%20you%20have%20been%20treated%20with%20propofol.
https://www.drugs.com/propofol.html
Propofol causes severe drowsiness and dizziness, which may last for several hours. You will need someone to drive you home after your surgery or procedure. Do not drive yourself or do anything that requires you to be awake and alert for at least 24 hours after you have been treated with propofol. Propofol side effects
https://www.ncbi.nlm.nih.gov/books/NBK430884/
Propofol Infusion Syndrome (PRIS): This is a rare but serious side effect of prolonged infusion of propofol (usually > 4mg/kg/hour for more than 24 hours). The syndrome presents as metabolic acidosis, hyperkalemia, hyperlipidemia, and rhabdomyolysis and may proceed to renal and cardiac failure and ultimately death.
https://pubchem.ncbi.nlm.nih.gov/compound/propofol
Approximately 70% of a dose is excreted in the urine within 24 hours after administration, and 90% is excreted within 5 days. Clearance of propofol ranges from 1.6 to 3.4 liters per minute in healthy 70 kg patients. As the age of the patient increases, total clearance of propofol may decrease.
https://www.virginialeenlaw.com/useful/question-how-long-after-propofol-can-you-drink-alcohol.html
The half-life of elimination of propofol has been estimated to be between 2 and 24 hours. However, its duration of clinical effect is much shorter, because propofol is rapidly distributed into peripheral tissues. When used for IV sedation, a single dose of …
https://www.pdr.net/drug-summary/Diprivan-propofol-1719.3436
The maintenance dose is usually continued for 12 to 24 hours and adjusted according to EEG results. The primary end-point is EEG burst suppression. After 12 to 24 hours, the continuous infusion of propofol is withdrawn gradually. If seizures recur, therapy should be resumed for …
https://www.apsf.org/article/the-propofol-safety-review/
The postoperative infection in these early cases was attributed to lapses in aseptic technique with risk factors that included “batch” preparation of propofol syringes for use throughout the day, reuse of syringes or infusion pump lines on different patients, use of propofol syringes prepared more than 24 hours in advance, transfer of prepared syringes between operating rooms or facilities, failure to wear …
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