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https://www.acc.org/latest-in-cardiology/articles/2020/01/27/07/42/management-of-pe
Jan 27, 2020 · However, PE is considered to be the third most common cause of cardiovascular death, with 60,000-100,000 deaths per year. 1-3 This is likely an underestimation because PE can result in unexplained sudden cardiac death. Treatment varies depending on the severity of the disease and the center's expertise and resources.
https://www.yeovilhospital.co.uk/wp-content/uploads/2016/01/PE-Guidelines.pdf
Page 6 of 12 5.4.2 CT pulmonary angio (CTPA) Diagnostic investigations for pulmonary embolism Ideally a CTPA should be performed within 1 hour in suspected massive PE, and 24 hours in non-massive PE (BTS – 2003). However, at this point in time, in this Trust, the
https://thorax.bmj.com/content/58/6/470
Jun 01, 2003 · Streptokinase, which in PE used to be given over 12 hours, works better in PE if given in 2 hours. 251, 252 Elegant experiments in dogs 253 have explained the clinical finding that thrombolysis is equally effective when given peripherally as when administered through a catheter positioned adjacent to the embolus 254; the latter requires femoral artery cannulation with a high incidence of local bleeding. 248, 255 Where there are absolute contraindications to thrombolysis—rarely …Estimated Reading Time: 9 mins
https://emcrit.org/ibcc/pe/
Sep 05, 2019 · 100 mg IV alteplase (tPA) over 2 hours has traditionally been considered as “full dose” thrombolysis, for use in massive pulmonary embolism. This dose was selected in an arbitrary fashion. There is no evidence supporting the use of this dose, as compared to a lower dose.Estimated Reading Time: 10 mins
https://www.aafp.org/afp/2017/0301/p295.html
Mar 01, 2017 · Wait 12 hours (CrCl = or > 30 mL per minute per 1.73 m 2) or 24 hours (CrCl < 30 mL per minute per 1.73 m 2) after the last dose of dabigatran before initiating a parenteral anticoagulant.Cited by: 19
https://www.bmj.com/content/370/bmj.m2177
Aug 05, 2020 · Pulmonary embolism is a common and potentially fatal cardiovascular disorder that must be promptly diagnosed and treated. The diagnosis, risk assessment, and management of pulmonary embolism have evolved with a better understanding of efficient use of diagnostic and therapeutic options. The use of either clinical probability adjusted or age adjusted D-dimer interpretation has led to a ...Cited by: 9
https://cks.nice.org.uk/topics/pulmonary-embolism/management/suspected-pulmonary-embolism/
For people with a Wells score of 4 points or less (PE unlikely), offer a D-dimer test with the result available within 4 hours: If the test result cannot be obtained within 4 hours, offer interim therapeutic anticoagulation while awaiting the result (if possible, choose an anticoagulant that can be continued if …
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