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https://pubmed.ncbi.nlm.nih.gov/10550134/
Purpose: Paclitaxel is an active drug for the treatment of breast cancer; however, the appropriate duration of administration is unknown. We assessed and compared the response rate, event-free survival, survival, and toxicity of paclitaxel 250 mg/m(2) delivered every 3 weeks as a 3-hour or 24-hour …Cited by: 210
https://pubmed.ncbi.nlm.nih.gov/7544025/
Paclitaxel 135 mg/m2 over 24 hours preceded carboplatin dosed to an area under the concentration-time curve of 7.5. Six planned courses were given every 3 weeks. Granulocyte colony-stimulating factor was introduced during the second and subsequent cycles, and paclitaxel increased 40 mg/m2/cycle (maximum, 215 mg/m2) in patients with absolute ...Cited by: 13
https://pubmed.ncbi.nlm.nih.gov/17072270/
Paclitaxel is generally administered at doses of 175-225 mg/m2 over 3 hours or 135-175 mg/m2 over 24 hours, every 3 weeks. The purpose of this study was to simplify administration and render it suitable and practical in the outpatient setting.Cited by: 4
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=40c0abf0-06ad-8658-a784-6554a540a768
Jun 19, 2019 · Paclitaxel administered intravenously over 24 hours at a dose of 135 mg/m 2 followed by cisplatin at a dose of 75 mg/m 2. 2) In patients previously treated with chemotherapy for carcinoma of the ovary, paclitaxel has been used at several doses and schedules; however, the optimal regimen is not yet clear (see CLINICAL STUDIES, Ovarian Carcinoma ...
https://www.pdr.net/drug-summary/Paclitaxel-paclitaxel-1299
135—175 mg/m2 IV over 3 hours or up to 250 mg/m2 IV over 24 hours every 3 weeks. Weekly paclitaxel at doses of 80—100 mg/m2 IV over 1 hour are under investigation. Studies of weekly doses have given paclitaxel for 3 consecutive weeks with 1 week off, 6 weeks consecutively with 2 weeks off, or weekly for >12 weeks continuously.
https://journals.sagepub.com/doi/pdf/10.1177/107327489500200112
over three or 24 hours has been com pleted, but the results ar~ not y.et available. The National Surgical Ad1u-vant Breast and Bowel Project is com paring response rates paclitaxel 250 mg/m 2 administered over three or 24 hours in metastatic breast cancer patients. 18 This group is also investi
http://www.adgosun.com/COAS/A50.pdf
over 24 hrs; this rate should be maintained for 2 hours. If no major reaction occurs, the rate should be in creased gradually over the next 6 hours to the original 24-hour rate. If the original HSR occurred after a negligible dose of paclitaxel, the full does should be readministered. If a substantial fraction of …
https://www.drugs.com/dosage/paclitaxel.html
Jun 23, 2021 · 135 mg/m2 IV over 24 hours followed by cisplatin 75 mg/m2 IV every 3 weeks For patients previously treated for cancer of the ovary (NOTE: This drug has been used at several doses and schedules; however, the optimal regimen is not yet clear): 135 mg/m2 IV over 3 hours every 3 weeks OR 175 mg/m2 IV over 3 hours every 3 weeks Comments:
https://chemocare.com/chemotherapy/drug-info/Paclitaxel.aspx
Paclitaxel is given over various amounts of times and in various schedules. There is no pill form of Paclitaxel. The amount of Paclitaxel and the schedule that it is given will receive depend on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated.
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