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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460300/
PVA-PEG hydrogels have been employed to heal acute burn wounds and also as drug delivery agents , , . However, as drug delivery carriers, the major drawback that is inevitably associated with hydrogels is the inefficacy to control the initial burst release of drugs.Author: Subhraseema Das, Usharani Subuddhi
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide …Author: Jianyu Li, David J. Mooney
https://onlinelibrary.wiley.com/doi/full/10.1002/adv.22119
Aug 14, 2018 · In the past, we developed chemically cross‐linked polyvinyl alcohol (PVA)‐based hydrogels that were synthesized through same polymerization method for delivery of single drug. 22 In this research work, an inimitable hydrogel system has been synthesized using itaconic acid, methacrylic acid, and polyvinyl alcohol. A stable system was developed through chemical cross‐linking, and two drugs were loaded to prepare combinatorial system for colonic delivery …Author: Orva Abdullah, Muhammad Usman Minhas, Mahmood Ahmad, Sarfaraz Ahmad, Kashif Barkat, Aousaf Ahmad
https://www.sciencedirect.com/science/article/pii/S0142941819320811
Hydrogels with injectability under mild condition are preferred in the field of biomedicine, especially for drug delivery and tissue engineering, because of the favorable carrier property in three-dimension, biocompatibility, low invasive and adaptable shape for administration.Author: Yining Sun, Ding Nan, Haiqiang Jin, Xiaozhong Qu
https://www.sciencedirect.com/science/article/pii/S1359029497801033
Hydrogels and drug delivery Nikolaos A Peppas Recent developments include the use of water-swollen, crosslinked biomedical polymers as carriers for the delivery of drugs, peptides and proteins, as targeting agents for site-specific delivery, or as components for preparation of …Author: Nikolaos A Peppas
https://pubs.acs.org/doi/full/10.1021/acs.jpcb.6b01381
PVA hydrogels are characterized for associated inflammatory response in adhering macrophages, antiproliferative effects mediated through delivery of cytotoxic drugs to myoblasts, and pro-proliferative activity achieved via presentation of conjugated growth factors to endothelial cells.Author: Bettina E. B. Jensen, Izaskun Dávila, Alexander N. Zelikin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630634/
Jun 20, 2019 · In 2003, Na-Mi et al. developed a film-forming soft hydrogel for transdermal delivery of testosterone using polyvinyl alcohol with a skin-permeation enhancer and an adhesive agent . Polyisobutylene was used as an adhesive agent in the gel to reduce the contact angle and surface energy [50,51]. The gel was observed for 2–3 min for forming a film after application, and the thin film …Author: Thao T. D. Tran, Phuong H. L. Tran
https://www.researchgate.net/publication/265846606_Modular_Hydrogels_for_Drug_Delivery
hydrogels are also limited for drug delivery applications due to the often quick elution of drug from their highly swollen. polymer matrices as well as the difficulty inherent in the injection of macroscopic hydrogels into the body. This paper. presents an overview to the advances in hydrogels based drug delivery.
https://www.tandfonline.com/doi/10.3109/10731199.2012.675337
(2012). Development of antibiotic and debriding enzyme-loaded PLGA microspheres entrapped in PVA-gelatin hydrogel for complete wound management. Artificial Cells, Blood Substitutes, and Biotechnology: Vol. 40, No. 5, pp. 345-353.
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