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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548250/
Jul 01, 2011 · In other words, they require pulsatile drug delivery system (PDDS). The pulsatile system is gaining a lot of interest, as the drug is released completely after defined lag time (Fig. 1). Pulsatile drug delivery is time and site-specific drug delivery, thus providing spatial and temporal delivery and increasing patient compliance.Author: Deepika Jain, Richa Raturi, Vikas Jain, Praveen Bansal, Ranjit Singh
https://www.slideshare.net/optimpharma/pulsatile-drug-delivery-system
Mar 01, 2012 · Development and evaluation of pulsatile drug delivery system using novel polymerThe aim of the present investigation was to develop a pulsatile drug delivery system based on an insoluble capsule body filled with theophylline microspheres and sealed with a swellable novel polymer plug isolated from the endosperm of seeds of higher plant Delonix ...
https://www.slideshare.net/bhavyamitta/pulsatile-drug-delivery-system-44699549
Feb 15, 2015 · What and why PDDS? Pulsatile drug delivery system is defined as the rapid and transient release of certain amount of drug molecules within a short time period immediately after a predetermined off-release period, i.e., lag time. Pulsatile drug delivery aims to release drug on programmed pattern i.e. at appropriate time and at appropriate site ...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulsatile-delivery
In particular, oral pulsatile drug release pertains to the burst delivery of drugs following a programmed pattern from the time of oral administration. For example, Ritalin LA capsule is a pulsatile delivery system that provides IR of 50% of the total dose upon oral ingestion followed by a burst release of the remaining drug after 4 hours. In ...
https://www.researchgate.net/publication/267829648_Pulsatile_Drug_Delivery_System_An_Overview
Pulsatile delivery system is necessary for diseases which show circadian rhythms in their pathophysiology [4, 5]. Ischemic heart disease constitutes a paradigmatic example of the importance of ...
https://www.ijpsonline.com/articles/pulsatile-drug-delivery-systems-an-approach-for-controlled-drug-delivery.pdf
The pulsatile effect, i.e., the release of drug as a “pulse” after a lag time has to be designed in such a way that a complete and rapid drug release should follow the lag Fig. 1: Drug release profiles from pulsatile drug delivery system a = release of drug as a “pulse” after a lag time, b = deliveringAuthor: Shweta Arora, J Ali, Alka Ahuja, Sanjula Baboota, J Qureshi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048537/
Pulsatile Release of Parathyroid Hormone from an Implantable Delivery System. ... Therefore, the development of a pulsatile delivery system that can precisely modulate PTH release is critical for its successful therapeutic utility in the clinical treatment of osteoporosis, overcoming limitations of the current treatment regimen (daily injectionAuthor: Xiaohua Liu, Glenda J. Pettway, Laurie K. McCauley, Peter X. Ma
https://www.pharmatutor.org/articles/pulsatile-drug-delivery-system-recent-advances-review
Current review article discussed the reasons for development of pulsatile drug delivery system, types of the disease in which pulsatile release is required, classification, advantages, limitation, and future aspects of pulsatile drug delivery system. Pulsatile delivery is defined as the rapid and transient release of certain amounts of drug ...
https://www.researchgate.net/publication/326010566_A_REVIEW_OF_PULSATILE_DRUG_DELIVERY_SYSTEM
Pulsatile drug delivery system is defined as the rapid and transient release of certain amount of molecules within a short time period immediately after predetermined off-release periods i.e. lag ...
https://www.jgtps.com/admin/uploads/HLfGVn.pdf
Pulsatile drug delivery system is gaining a lot of interest and attention now a day. Though most delivery system is designed for constant drug release over a prolonged period of time, PDDS are characterized by a programmed drug release, as constant blood level may not …
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