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http://www.aradigm.com/technologies.html
Aradigm's AERx pulmonary drug delivery technology provides performance that is at the leading edge in terms of efficiency of delivery to the lung and reproducibility of dosing – not just in the laboratory but also as determined in many human clinical trials.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
During the past decade pulmonary drug delivery technology advanced substantially due to several inventions in propellants, excipients, and device technologies. The large surface area of the human lung, along with its rich blood supply, rapid onset of drug action with high bioavailability, and other physiological advantages, make it a potential route for treating asthma, COPD, and other pulmonary disorders.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334339/
Feb 12, 2015 · Pulmonary drug delivery is an attractive route of administration for diverse entities including micro and macromolecules such as vaccines, DNA, cytokines, antibodies, and hormones.16 Therefore, it is essential that the hardware technology of inhalers meets the needs of the pulmonary delivery of such diverse molecules. Devices should be ...Author: Mariam Ibrahim, Rahul Verma, Lucila Garcia-Contreras
https://www.ncbi.nlm.nih.gov/pubmed/32130023
Mar 16, 2020 · For this reason, there are several ongoing technical innovations to improve inhaler devices.Areas covered: Progress in pulmonary drug delivery device technology is examined, focusing on innovations in pressurized metered dose inhalers, dry powder inhalers, nebulizers, and soft mist inhalers.Expert opinion: Both formulation improvements and new ...Author: Mario Cazzola, Francesco Cavalli, Omar S Usmani, Paola Rogliani
https://www.thefreelibrary.com/Novel+pulmonary+delivery+technology.-a0199464520
Jan 01, 2007 · The technology produces low velocity clouds of uniformly sized particles with extremely high efficiencies, enabling consistent delivery of drug throughout the lungs. The non-pressurized aerosol mist is easily inhaled using the patient's normal inspiratory breath.
http://www.pharmtech.com/four-challenges-pulmonary-drug-delivery
Sep 01, 2017 · Pulmonary drug delivery is becoming an increasingly used non-invasive route of administration to treat widespread and debilitating lung diseases. However, when developing treatments that rely on this delivery mechanism, it is important to consider the …
http://www.pharmtech.com/pulmonary-drug-delivery-particle-engineering-inhaled-therapeutics
Feb 02, 2014 · In terms of the technology, pulmonary drug delivery is determined by the nature of the API, the formulation, the device, and their functional performance in aerosolization. An important feature of inhaled drugs is the particle size of the dose components, particularly the active molecule.
https://www.pharmatutor.org/articles/pulmonary-drug-delivery-a-review
Pulmonary delivery of drug has become an attractive target and of tremendous scientific and biomedical interest in the health care research area as the lung is capable of absorbing pharmaceuticals either for local deposition or for systemic delivery.
https://innovareacademics.in/journal/ijap/Vol2Issue4/126.pdf
Agglomerated vesicle technology for pulmonary drug delivery These particles are of multimicron sized chemically linked agglomerates of core nanoparticles. The links between the nanoparticles can be either permanent (e.g. carbonyl) or cleavable (e.g. disulfide or ester). Complex agglomerate structures can be
https://www.in-pharmatechnologist.com/Article/2014/09/25/Acorda-gains-pulmonary-drug-delivery-tech-in-525-Civitas-deal
Tech Protection The Arcus platform is an aerosol delivery system which allows precise delivery of large quantities of drug per inhalation administered using the firm’s breath-actuated inhaler and, unlike other pulmonary systems, does not require carrier particles or supplemental energy to disperse.
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