Pulmonary Delivery Of Opioids

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Pulmonary delivery of opioids as pain therapeutics ...

    https://www.sciencedirect.com/science/article/pii/S0169409X06001487
    Pulmonary opioid delivery, on the basis of the fact that small molecular entities can be rapidly and completely absorbed from the peripheral lung, poses a unique opportunity for the treatment of severe (breakthrough) pain, which currently is treated with intravenous therapy.Author: Stephen J. Farr, Babatunde A. Otulana

Pulmonary delivery of opioids as pain therapeutics ...

    https://www.researchgate.net/publication/6724978_Pulmonary_delivery_of_opioids_as_pain_therapeutics
    Pulmonary opioid delivery, on the basis of the fact that small molecular entities can be rapidly and completely absorbed from the peripheral lung, poses a unique opportunity for the treatment of ...

Pulmonary Drug Delivery - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
    Yousef Javadzadeh, Shadi Yaqoubi, in Nanostructures for Drug Delivery, 2017. Abstract. Pulmonary drug delivery has attracted tremendous interest in the past two decades. In order to get both local and systemic effects, lungs as the main part of the respiratory system offer an interesting route to noninvasive drug administration.

Pulmonary administration of aerosolised fentanyl ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1873979/
    Sep 23, 1997 · Pulmonary drug delivery is a promising noninvasive method of systemic administration. Our aim was to determine whether a novel breath-actuated, microprocessor-controlled metered dose oral inhaler (SmartMist™, Aradigm Corporation) could deliver fentanyl in a …Author: Laurence E. Mather, Annie Woodhouse, M. Elizabeth Ward, Stephen J. Farr, Reid A. Rubsamen, Lorne G. ...

Pulmonary delivery of opioids as pain therapeutics ...

    https://www.deepdyve.com/lp/elsevier/pulmonary-delivery-of-opioids-as-pain-therapeutics-D06lgZ9yLj
    Oct 31, 2006 · Pulmonary delivery of opioids as pain therapeutics Pulmonary delivery of opioids as pain therapeutics Farr, Stephen J.; Otulana, Babatunde A. 2006-10-31 00:00:00 Pulmonary opioid delivery, on the basis of the fact that small molecular entities can be rapidly and completely absorbed from the peripheral lung, poses a unique opportunity for the treatment of severe (breakthrough) pain, which ...

Palliative care for patients with’pulmonary fibrosis ...

    https://erj.ersjournals.com/content/erj/52/6/1802086.full.pdf
    Palliative care for patients with pulmonary fibrosis: symptom relief is essential Kathleen Lindell1 and Ganesh Raghu2 Affiliations: 1Div. of Pulmonary, Allergy and Critical Care, Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, PA, USA. 2Center for Interstitial Lung Disease, University of Washington, Seattle, WA, USA.Author: Kathleen Lindell, Ganesh Raghu

Effects of Opioids on Breathlessness and Exercise Capacity ...

    https://www.atsjournals.org/doi/full/10.1513/AnnalsATS.201501-034OC
    Jul 01, 2015 · Rationale: Patients with chronic obstructive pulmonary disease (COPD) commonly suffer from breathlessness, deconditioning, and reduced health-related quality of life (HRQL) despite best medical management. Opioids may relieve breathlessness at rest and on exertion in COPD. Objectives: We aimed to estimate the efficacy and safety of opioids on refractory breathlessness, exercise …Author: Magnus Ekström, Fredrik Nilsson, Amy A. Abernethy, David C. Currow

The Effects of Opioids on the Lung SpringerLink

    https://link.springer.com/article/10.1007%2Fs12016-013-8373-z
    May 01, 2013 · Many complications can occur with multiple different opioids, such as non-cardiogenic pulmonary edema, while many of the complications are unique to the opioid used as well as the route of administration. This review focuses on the pulmonary complications associated with opioid use and abuse, but opioids can affect nearly every organ system.Author: Joshua B. Radke, Joshua B. Radke, Kelly P. Owen, Mark E. Sutter, Jonathan B. Ford, Jonathan B. Ford,...

Advanced Chronic Obstructive Pulmonary Disease: Innovative ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756889/
    Nov 05, 2015 · Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide and results in an economic and social burden that is both substantial and increasing. By the year 2020, COPD will be the third leading cause …Author: Hai-Xia Zhou, Xue-Mei Ou, Yong-Jiang Tang, Lan Wang, Yu-Lin Feng

Engineered PLGA nano- and micro-carriers for pulmonary ...

    https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.2042-7158.2012.01486.x
    obstructive pulmonary disease (COPD) and cystic fibrosis (CF),an effective‘local’delivery (i.e.centrally rather than at the periphery) of the drug is necessary.[3,4] Strategies for tar-geting drugs to the alveoli have become increasingly impor-tant, as many inhaled drugs are developed either to beAuthor: Francesca Ungaro, Ivana d' Angelo, Agnese Miro, Maria I. La Rotonda, Fabiana Quaglia

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